Unbound dolutegravir plasma concentrations unchanged in pregnancy and standard dosing crosses the placenta in placental perfusion model
29 June 2018. Related: Conference reports, Pregnancy, PK and drug interactions.
PK Workshop 19th 2018 Baltimore
Etravirine dispersible paediatric tablet has greater bioavailability when dispersed in water compared to swallowed whole
29 June 2018. Related: Conference reports, Paediatric care, PK and drug interactions.
Reduced exposure to elvitegravir in pregnancy: results from the PANNA Network
29 June 2018. Related: Conference reports, Pregnancy, PK and drug interactions.
Rifabutin dosed 2.5 mg/kg daily with lopinavir/r in children achieves comparable exposure to adults
29 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.
No clinically relevant reduction in oral cabotegravir when co-administered with rifabutin
29 June 2018. Related: Conference reports, PK and drug interactions.
Boosted darunavir 800/100 mg twice daily might overcome interaction with rifampicin
29 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.
Efavirenz side effects and other drug-drug interactions are common in Ugandan cohort
29 June 2018. Related: Conference reports, PK and drug interactions, Side effects.
19th International Workshop on Clinical Pharmacology, 22–24 May 2018, Baltimore
8 June 2018. Related: Conference reports.
Dolutegravir 50 mg twice daily sufficient with rifampicin but levels reduced significantly with 100 mg once daily
8 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.
Vaginal ring reduces efavirenz but not atazanavir exposures
8 June 2018. Related: Conference reports, PK and drug interactions.