Question

Can TLD be used as PEP?

5 January 2022. Related: All topics, HIV transmission, PEP/PEPSE.

Can TLD help someone who has been in contact with an HIV positive person to prevent them from contracting HIV before 72 hrs?

Answer

Answer: Josh Peasegood

Hi, how are you?

Yes you can. TLD is a combination that can be used as PEP and for the management of active HIV infection. PEP stands for post exposure prophylaxis. PEP is used to prevent established infection after exposure.

TLD is a first choice recommendation for PEP. The course lasts 28 days following a high risk exposure. It is only used in cases where the exposure was within 72 hours. After this, regardless of what drug is prescribed, PEP will not work.

However, if your partner was using effective HIV treatment (ART) , you will not be at risk. Having an undetectable viral load on ART means HIV is not a risk. Please see:
i-base.info/u-equals-u/

Please see this link for more information about PEP:
https://i-base.info/qa/factsheets/pep-faq

If you have any more questions please ask,

Josh.

126 comments

  1. Sharon •

    At the hospital they gave me TLD for 14 days only I went to another hospital they gave me La75 as pep I wanted to find out if it’s one and the same

  2. Josh Peasegood •

    Hi 3D5ON, after 72 hours the effectiveness of PEP is not evident. Unfortunately after 72 hours PEP is not likely to have an effect. However if you feel more comfortable taking a course of PEP there is no harm in continuing to do so. Do you know if the person with HIV was on treatment or if they had an undetectable viral load?

  3. 3D50N •

    I accidentally Pricked myself with a needle in used on an HIV person……… I took my first dose of TLD at exactly 4hour after the 72 hour elapsed….

    Am I still safe???

  4. Josh Peasegood •

    Hi Solo, it is best to take this medication to a pharmacist to be identified. It is not possible to identify it from the engraved code.

  5. Solo •

    What about this drug written la75 is it TLD

  6. Josh Peasegood •

    Hi Linkie, yes you are safe. Even if your partner was not being truthful (why do you think this?), being on PrEP will prevent any risk of transmission.

  7. Linkie •

    Hello
    I am on prep and I slept with someone using acriptega, he is not being honest what he uses it for . I take my prep as prescribed
    Do u think m safe?

  8. Josh Peasegood •

    Hi Nkosinathi, TLD is not used as PrEP because it contains three drugs and PrEP only needs two drugs (usually tenofovir and emtricitabine).

  9. Nkosinathi •

    Can I Used TLD as a form of PrEP? This is because it would be easier for to get TLD than It would be if I was to get the most recommended prep drugs

  10. Josh Peasegood •

    Hi Mary, starting PEP so soon means transmission is not likely. Do you also know if this person was on ART/undetectable? If so the risk of transmission is further reduced.