Q and A

Question

Can TLD be used as PEP?

Can TLD help someone who has been in contact with an HIV positive person to prevent them from contracting HIV before 72 hrs?

Answer

Hi, how are you?

Yes you can. TLD is a combination that can be used as PEP and for the management of active HIV infection. PEP stands for post exposure prophylaxis. PEP is used to prevent established infection after exposure.

TLD is a first choice recommendation for PEP. The course lasts 28 days following a high risk exposure. It is only used in cases where the exposure was within 72 hours. After this, regardless of what drug is prescribed, PEP will not work.

However, if your partner was using effective HIV treatment (ART) , you will not be at risk. Having an undetectable viral load on ART means HIV is not a risk. Please see:
i-base.info/u-equals-u/

If you have any more questions please ask,

Josh.

120 comments

  1. Mary

    Hi..I am mary..I had a needle prick injury on my palm (hand) (but it was not deep it was on the surface) while vaccinating someone who’s HIV positive. And immediately I started pep within 8hrs.what are the chances I could be or not infected?

  2. Josh Peasegood

    Hi Puleng, depending the frottage that you partook in, there is no risk of transmission – skin to skin contact does not transmit HIV. For this reason your exposure would is considered low – zero risk. HIV transmission risk: https://i-base.info/guides/testing/risks-for-transmission

    Being nauseas and tired only are not signs of HIV. Are you experiencing any other symptoms? and at what time of the day are you taking TLD:

  3. Puleng

    Greetings,

    I’m a female & I have decided to go on TLD PEP after an incidence of unprotected frottage with my partner. I feel a bit nauseas & tired after 12 days of being on PEP. Should I be worried?

  4. Josh Peasegood

    Hi Mary, this is considered a very low risk exposure – if this was an exposure at all. It is still more likely that your partner is HIV negative. In the UK this is not a case that would require PEP.

    Please follow this link for more information: https://i-base.info/qa/factsheets/hiv-transmission-and-testing

  5. mary

    Hi I had sex with someone but I don’t know their status..we were to go for a test but he ghosted me meaning maybe his intention was to infect me. There was no penetration without a condom but there was rubbing of his manhood on my vagina.should I start the pep medication?

  6. Josh Peasegood

    Hi Ema, testing positive means that this person is HIV positive. It is very rare to get a false positive. This means that while this person was not on treatment, having sex without a condom would carry a risk of transmission.

    Please see here: https://i-base.info/guides/testing/risks-for-transmission

  7. Ema

    Some one started PEP when he had not tested knowing is HIV neg according to previous test. After one week he tested positive. Can those results be positive?. If someone had sex with him, is it high risk?

  8. Josh Peasegood

    Hi GrandXeno, HIV transmission is not guaranteed for each sexual encounter. There are a number of factors that change the risk of transmission. These can be found here: https://i-base.info/guides/testing/risks-for-transmission

    Now that you are aware of your wife’s status, using a condom will prevent any further risk. Is she starting treatment? If she is, risk is reduced to baby and soon there will be no risk to you regardless of using a condom. This is explained here: https://i-base.info/u-equals-u/

  9. GrandXeno

    Hello, am bit confused i went with my pregnant wife yesterday for a checkup they tested us both and i was negative while she was positive. My question is I have been sleeping with her for some time now and have some symptoms of HIV here and there!!Am always getting tested think it was for the fourth time now and still negative. How is it possible because we only found out yesterday that she was positive and not on meds!?

  10. Josh Peasegood

    Hi Mae, this is not a risk for transmission. There is no reason to be on PEP. HIV cannot be transmitted in this way. Your abdominal symptoms are not related to HIV – this is far too quick to be suggestive of HIV.

    Please follow this link for more information: https://i-base.info/qa/factsheets/hiv-transmission-and-testing

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