Q and A

Question

I just started odimune and have difficult side effects.

Hi,
I started odimune last night and after two hours I felt like some things were crawling on my face,my ears became painful,my head feels like its going to explode and it went on until today. I can’t work please help.

Answer

Hello,

Thanks for your email. I’m sorry to hear about these difficult side effects you are experiencing.

It is very normal to have difficult side effects in the first few days and weeks of treatment. Some people may find that they need to take a few days off work while this is most difficult. Are you able to do this?

Most side effects will get better or go away after a few weeks. If these are very severe and you are worried you should talk to your doctor. If you have any rash you should show this to your doctor. You should be able to access some treatment to make these side effects easier- for instance painkillers for the headache.

There are a small percentage of people who cannot tolerate certain drugs.  You could be one of these people. If the side effects do not go away after a month or so, then you need to discuss this with your HIV doctor. They can usually replace the drug, which is causing the side effect.

Please see our side effects guide for more information.

100 comments

  1. Lisa Thorley

    Hi Vince,

    If your friend is weak and unwell he needs to see a doctor. He also needs to restart taking ARVs. As to how this happens, I really can’t advise you as I don’t know why your friend defaulted or what state of mind they are in.

  2. Vince

    I have a friend who defaulted on Odimune and he is now very weak. How do we get him back on

  3. Lisa Thorley

    Hi Mmasebudule,

    If your partner is on treatment (which is sounds like he is) as long as his viral load is undetectable, there’s no risk to you. Please see here: https://i-base.info/u-equals-u/

    With regards to how you bring up the subject of HIV, only you can answer this as it’s you who knows your partner. Firstly you need to be clear about what it is that you want. It might help to know that lots of positive people are in relationships with negative people and HIV isn’t an issue, which is shouldn’t be.

  4. Mmasebudule

    I’ve just found out my partner is using Odimune.
    We always had protected sex, my questions is, how do I make sure I don’t get infected by him? Should the condom break or something.
    How can I ask him about his Odimune and his HIV status as he didn’t mention anything to me yet. I’ve always heard rumours about his status and I waited for him to tell Me, still nothing yet.
    We’ve recently started dating 2 months ago.

    I am worried because I am not sure if it’s safe for me to be in a relationship with him ? Or can I just move on ? Or must I also take some meds in case anything happens ?

  5. Lisa Thorley

    Hi Bongie,

    Odimune is a generic version of an ARV called Atripla, please see here: https://i-base.info/guides/1561 Ideally this medication should be taken at night. However, it might be possible for you to take it in at another time, you’ll need to see if you have side effects if you take it earlier than evening/night.

  6. Bongie

    Hi the odimune I can take any time or what can I do

  7. Lisa Thorley

    Hi Phily,

    What you’ve been told isn’t true. It’s perfectly safe to take Odimune if you’re pregnant. As you’re yet to start medication you may find the following helpful: https://i-base.info/guides/starting as well as the our guide for women: https://i-base.info/guides/pregnancy

  8. Phily

    I’m so scared to eat this pills adimune coz people they said if u get pregnant I gonna get problem of chikd

  9. Lisa Thorley

    Hi Khanya,

    Thanks for your question.

    You say you have hearing problems and headaches since starting HIV meds. Also, that you have been on TB meds for the same time and that these have just finished.

    If I have this right, then, have you told your doctor about this? If yes, what did they say? If no, then please tell them now. It is always important to tell your doctor about any problems, as soon as they start.

    Hearing problems are sometimes caused by TB medicines. Please see here: https://www.sciencedirect.com/science/article/pii/S095461110600045X If this is the case, this might get better now you no longer need to take these.

    If the problems continue though, your doctor could look at whether this might be linked to HIV drugs. Even though this is not common, changing to a different combination might help.

    Your doctor also needs to look at your eyes as well as talk to you about the itching that you’re experiencing.

  10. Khanya

    I’m using tribus odimune and atroiza, now its itching and difficult to sleep. I’ve painful eyes sounds in my ears. I started using ARVs in Aug 2019. I’ve just finished TB meds.

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