Q and A

Question

Is there a difference between Atripla, Odimune, Rizene and Tribuss etc

Hi

I started with Atripla, then received Odimune and now I have been given Tribuss from my provider.

I have never had side effects. How safe is it for me to take Tribuss?

I’m afraid it might change how I look. Is it the same as the two I have already been taking?

Answer

Hi

Tribuss and Odimune are generic versions of the fixed dose combination pill Atripla. These drugs have different names because they are made by different manufacturers.

Each version contains the same doses of three drugs. These are tenofovir, FTC and efavirenz.

There are no safety concerns from switching from one version to another.

Although some HIV meds have been linked to body shape changes, this is not commonly reported for any of these drugs. One exception, generally rare, is that efavirenz has been linked to weight gain in breast tissue – also called gynaecomastia (GYE-na-co-MAS-tee-ah).

See:

Efavirenz-associated gynaecomastia reported to the national HIV and TB healthcare workers hotline in South Africa

Dihydrotestosterone for HAART-associated breast enlargement in men

This answer was updated on 12 July 2020 from an original question on 21 May 2013.

134 comments

  1. Josh Peasegood

    Hi M, what side effects are you experiencing? If possible it would be advised to remain on the same combination for the duration of PEP.

    Some side effects can be managed with other treatments. Have you mentioned what you are experiencing to your doctor? They may suggest additional medications to help ease the side effects you are currently experiencing.

  2. m

    can u switch meds on pep? can u switch between different formulations while on it? for example due to side effects or is it better to tough it out for a month.

  3. Josh Peasegood

    Hi Forbes, I am sorry but I do not recognise Triemsta. Where did you get this from? Are you able to ask the pharmacist if it is the same as Trisbuss?

  4. Forbes

    Are tribuss and triemsta table the same?

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