Question
Is there a difference between Atripla, Odimune, Rizene and Tribuss etc
12 July 2020. Related: All topics, Changing treatment, Side effects, South Africa.
Hi
I started with Atripla, then received Odimune and now I have been given Tribuss from my provider.
I have never had side effects. How safe is it for me to take Tribuss?
I’m afraid it might change how I look. Is it the same as the two I have already been taking?
Answer
Hi
Tribuss and Odimune are generic versions of the fixed dose combination pill Atripla. These drugs have different names because they are made by different manufacturers.
Each version contains the same doses of three drugs. These are tenofovir, FTC and efavirenz.
There are no safety concerns from switching from one version to another.
Although some HIV meds have been linked to body shape changes, this is not commonly reported for any of these drugs. One exception, generally rare, is that efavirenz has been linked to weight gain in breast tissue – also called gynaecomastia (GYE-na-co-MAS-tee-ah).
See:
Dihydrotestosterone for HAART-associated breast enlargement in men
This answer was updated on 12 July 2020 from an original question on 21 May 2013.
Hi Lahos, there is no need to be worried. These are the same medication. They have different names because they have been made by different manufacturers but they still contain the same ingredients. This question has been answered previously here: https://i-base.info/qa/16135
Hi.. my Dr prescribed me tribuss but at pharmacy they gave trenvir should I be worried?
Hi Nkululeko, what is your husbands viral load? Trenvir and TLD are different types of HIV medication, involving different ‘classes’ of drugs – this means the drugs work differently. TLD is often better tolerated than Trenvir. It is possible that this will help with your husbands viral load but I can’t comment without knowing what it is.
My husband has been using trenvir for 3 years his viral load was always high today they changed him to LTD is that going to help
Hi Sindisiwe, Atroiza and Acriptega are different medications however they both work to manage HIV. They contain different combinations of drugs with the main difference being Atroiza containing efavirenz and Acriptega containing dolutegravir. This switch is becoming quite common as Acriptega has fewer side effects and people tolerate the medication better. It is possible to cause insomnia though so taking earlier in the day would help alleviate this. Switching from Atroiza to Acriptega will not interfere with your viral load.
Hello I need to know if acriptega and atroiza are the same. Because at the clinic they use to give me the atroiza but they transfer me to clicks, so I went to collect my parcel when I opened it I found the acriptega. Now I’m confused.
Hi Thandiwe,
It sounds like you were taking a generic version of Atripla, please see here: https://i-base.info/guides/1561
The medication that you’re taking now differs because it contains different compounds. Acriptega contains tenofovir disoproxil, lamivudine and dolutegravir. Whereas Atripla contains- efavirenz + tenofovir DF + FTC
Many people are being switch to a dolutegravir based regime as it has less side effects than Atripla. It does however need to be taken in the morning.
I used to take 1 at night now i have been changed to acriptega that i take 1 in the morning . Whats the difference between the two?
Hi Lux,
The medication that you’ve been given (the odiume) is different to what you’ve previously been taking.
Odimune is a generic version of an ARV called Atripla, please see here: https://i-base.info/guides/1561
Where you told why you were being changed?
Since switching to your new meds have you had any side effects?
Hi I have been using luvigen pills and now they gave me odimune pills. Is it ok, or not good?