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IPERGAY PrEP study shows early efficacy in protecting gay men from HIV: all participants to switch to active drug

Simon Collins, HIV i-Base On 29 October 2014, French and Canadian researchers announced early efficacy of a PrEP study to protect gay men from catching HIV. This has led to a change in the study design. [1] The IPERGAY study is …

The PROUD study: access to PrEP in the UK to prevent HIV

At the end of last week I posted two new articles on the i-Base website. The first was an announcement about changes to the PROUD study. The second was a Q&A page about the change and about PrEP in the …

Q&A on PrEP in the UK and changes to the HIV PROUD study

NOTE: Please see this updated information about the PROUD results and access to PROUD in the UK. https://i-base.info/uk-proud-study-to-provide-prep-earlier-than-expected The following Q&A was produced by i-Base about PrEP in the UK including recent changes to the PROUD study. Participants in the …

UK PROUD study to provide PrEP earlier than expected: planned follow-up in this HIV prevention study to continue for two years

Important news for PrEP in the UK

HIV and young gay people in London: two short online videos

More a plug for two new online videos than a blog, these links relate to a public event held in Soho a couple of weeks ago. The first video is 12 minutes long and edits interviews with five young gay …

Introduction to Combination Therapy (Arabic)

Please click title link for the download page.

September/October HTB now online

Reports from the 54th ICAAC and IAS 2014 conferences, newly approved drugs for HIV and hepatitis C, new UK guidelines for pregnancy and PEP, plus a potential new approach for PML…

UK changes PEP meds: raltegravir replaces PIs

The UK has dropped the use of protease inhibitors (PIs) in combinations for Post Exposure Prophylaxis (PEP). This refers to when an HIV negative person uses HIV drugs for one month immediately after a risk for HIV – usually a …

HIV, gay men and drug use: ASTRA study and comment in The Lancet HIV

A research group I am involved with has just had a paper published in the new online publication The Lancet HIV. This paper is available free in full. [1] This is interesting for compiling results from one of the biggest …

July/August HTB now online

Ten reports from AIDS 2014, coverage from paediatric and INTEREST workshops, London guidelines, dolutegravir access in the UK, plus lots more…

HIV+ survey on a cure: please support with 10 minutes

This short survey is looking for community views from the UK and internationally to help shape future research

IAS 2014: news from Melbourne

Short reports and links to news at the 20th World AIDS Conference: cure research, PrEP (do you swallow?), pipeline report, HIV and children, HIV-related complications, activists protest Gilead’s price for sofosbuvir and global TasP…

Pipeline report 2014

Latest review of latest developments in HIV, HCV and TB: pipeline drugs, vaccines, cure strategies and diagnostics

Avoiding and managing side effects (Macedonian

Please click title link for the download page.

New ARV prescribing guidelines for London (2014)

Broadly good, but a few surprises: raltegravir alternative to efavirenz, limited use of generics, no need to switch stable patients…

Latvian guides now include HIV and pregnancy

A new Latvian translation of the i-Base guide to HIV, Pregnancy and Women’s Health is now online. This is the fourth i-Base guide to be translated into Latvian, in collaboration with Association HIV.LV and the EATG COPE project. HIV, pregnancy …

START study open DSMB report (May 2014)

The latest open report from the Data and Safety Monitoring Board (DSMB) for the international randomised START study is now online. START looks at the risks and benefits of immediate treatment (at any CD4 count above 500 cells/mm3) compared to …

Generic ARVs in the UK – background paper for drug commissioning

Leaflet in PDF format (82 Kb) New commissioning guidelines for London – April 2014. Introduction by i-Base This paper was originally drafted in 2012 as a discussion paper for the London HIV Consortium HIV and Drugs sub-committee, which I have been …

May/June HTB now online

Reports from EASL, BHIVA and CROI: new hepatitis C drugs, including pricing and UK access; ARVs in pregnancy; early use in babies; tenofovir in Zambia; US guidelines for treatment and PrEP; all this and more…

SCART study: selumetinib as potential treatment for HIV-related KS

SCART is a UK study for HIV-related Kaposi’s Sarcoma (KS). It uses an experimental cancer drug called selumetinib. KS is a type of cancer that is more common in HIV positive people although it is much less common now that …

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