October 2012

Contents

Editorial

• Volume 13 Number 9/10 September/October 2012

In memory

• Jerome Horwitz dies at 93

Supplements

• AIDS 2012: a non-technical review of the 19th IAS Conference

Conference reports

• 52nd International Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 9-12 September 2012, San Francisco

• Study summaries from ICAAC 2012

• Antiviral activity in vitro with S/GSK1265744

• Efavirenz interaction studies with TB compounds bedaquiline and delamanid

• 19th IAS World AIDS Conference, 22–25 July 2012, Washington

• HPTN-052: clinical advantages from earlier treatment

• Hormonal contraception and the risk of HIV acquisition

• Towards an HIV cure: Early developments reported at IAS, part 2

• Online video interviews between researchers and activists

Antiretrovirals

• FDA approves Quad in US: price may prohibit UK access

• Merck acquires CMX157 and EFdA and starts phase 2 study for new NNRTI

• Roche to discontinue production of nelfinavir and saquinavir 200 mg hard capsules

Treatment access

• FDA approval of generic ARVs

• Free HIV treatment in the UK for all, irrespective of residency status

• Robin Hood Tax begins in France

• Novartis case enters Indian Supreme court

• India: Bayer stay order against compulsory licence denied

PK and drug interactions

• Ritonavir significantly increases exposure to colchicine (gout)

• Ritonavir interaction with quinine is clinically insignificant but may warrant caution

• Case report: fluticasone, fluconazole and ritonavir interactions

Guidelines

• UK Standards for HIV Care online for comment (2012)

• HIV in England to remain as nationally commissioned specialist service

• US guidelines include Stribild (Quad) as alternative rather than preferred option for treatment naive adults (2012)

• IAS USA update adult ARV treatment guidelines (2012)

Side effects

• Increased incidence of ischemic stroke amongst HIV positive cohort

TB coinfection

• Costs for rapid TB test reduced by 40%

• Important advances in TB drug development

Virology

• Discord controllers: characterising a new viremic controller phenotype

PDFs

• Volume 13 Number 9/10 September/October 2012 PDF