Question
What are the side effects of TLD?
6 January 2022. Related: All topics, PEP/PEPSE, Side effects, Starting treatment.
Hi guys, I recently had sex with someone who was HIV positive. The next day I went to the clinic and they gave me PEP. I am currently on TLD but I am experiencing a stuffy nose, dry mouth and sore throat. I have little red spots on my legs, like a rash I don’t know if this are side effects or not. Please help.
Answer
Hi, how are you?
TLD is a combination medication. It includes dolutegravir, Lamivudine and tenofovir. As such any side effects are attributed to these medications. Stuffy nose, dry mouth and a sore throat are not a side effect. It is possible to cause a skin reaction and this should be checked by a doctor – the rash on your leg.
The common side effects for dolutegravir include: anxiety, depression, diarrhoea, fatigue, flatulence, stomach discomfort, headache, nausea, skin reactions, sleep disorders, vomiting.
The common side effects for lamivudine include: tummy pain, anaemia, lack of energy, diarrhoea, dizziness, fever, flatulence, headache, insomnia, nausea, low white blood cells, skin reactions, vomiting.
The common side effects for tenofovir include: abdominal pain, anaemia, tiredness, diarrhoea, dizziness, fever, flatulence, headache, insomnia, nausea, low white blood cells, skin reactions, vomiting.
These are the common side effects as listed by the BNF. You should note that while these are all common, they are not common together. It is also common for side effects to only be experienced in the first few weeks of starting medication while your body gets used to it. Common also means that it can be experienced by as few as 1 in 100 people.
Josh.
Hi Terry, how long have you been experiencing these symptoms? Did they start when you began TLD or have they come on since then?
How are you sleeping? TLD can cause problems sleeping. If you are not sleeping well this could be the reason for these side effects. Have you tried taking TLD in the morning before?
Hi have been on TLD for a year now I take my meds at night am experiencing alot of dizziness, fatigue,weakness in the body ,anxiety attacks,headache, neck pain ,what could be the problem plz?
Hi Rennie, how long have you been experiencing this dizziness? and when did you start taking TLD?
Hi I’m on TLD treatment I suffer a lot of dizziness Is it possible that this dizziness will go away
Hi Tiny, has your sister gone to see a doctor about this rash? As it started so soon after starting treatment it should be checked that she is not allergic to the medication. Has the allergy medication made any difference to this rash?
My sister just started TLD 2 days ago have rash all over her body including face, hands, head even under her foot small red rash, she’s pregnant and not treating with anything since she’s told no medication for pregnant women only allegex and once a day, how long is this gonna take?
Hi Stella, it is good that you are now feeling better. What has your doctor suggested?
have been on treatment over ten years now, the symptoms started late last year, it’s not a constant symptoms. the epistle come and go. yes have discussed with my Dr. have add well woman supplement to my diet… feeling better now.
Hi Stella, I am sorry to hear that you have this symptoms. How long have you had them? and how long have you been taking TLD? Unfortunately there are no vitamins that can help with this. Vitamins are not used to treat symptoms. They are only used to supplement a diet if it is not balanced and lacking nutrients/vitamins. Have you spoken with a doctor about this? and what time of the day do you take your treatment?
please l am on TLD ,now am having weakness in muscle , fatigue… please any vitamin that I can be taking to manage this condition? I would be glad if prescriptions can be given…thank you