Q and A

Question

What are the side effects of TLD?

Hi guys, I recently had sex with someone who was HIV positive. The next day I went to the clinic and they gave me PEP. I am currently on TLD but I am experiencing a stuffy nose, dry mouth and sore throat. I have little red spots on my legs, like a rash I don’t know if this are side effects or not. Please help.

Answer

Hi, how are you?

All meds can cause mild or minor side effects in some people but not everyone will get these side effects. Most of the side effects listed with the drug information only affect a percentage of people who use these meds.

This means nearly every medicine has a daunting list of potential side effects, but in practice you are unlikely to get any or only one or two.

Please see this link for info on PEP including side effects:

https://i-base.info/qa/factsheets/pep-faq

114 comments

  1. Josh Peasegood

    Hi Ndlovu, TLD does not cause pain in your feet. Has anything else changed in the last few weeks that could have caused this? and for how long have your feet been painful?

  2. Ndlovu

    Hi. I ve been on Tld for 2 weeks from today and my feets are so painful undernearth is that the effects ,also i was having headache but i am okay

  3. Josh Peasegood

    Hi Christina, have you been experiencing insomnia since starting TLD? Have you mentioned this to your doctor? As you are still having trouble sleeping when taking TLD in the morning, it may be appropriate for you to switch medication depending on what is available in your country.

    TLD does not cause the pain you have mentioned. You will need to speak with your doctor seperately about this as it will not be linked with your treatment.

  4. Christina

    Hi im taking my tld in the morning but still experience insomnia
    I have shoulders pain n heels pain what can be the problem and also my feed are swelling
    Ive been on tld since 2020

  5. Simon Collins

    Hi Samuel, thanks.

    Are you HIV positive? I ask because TLD is sometimes used as treatment and sometimes for prevention.

    If you are HIV positive, then it would be good to know your CD4 count.

    If your CD4 count started very low – ie less than 100 or less than 50, these symptoms might be related to another infection. This makes it important to tell your doctor straight away.

    Please tell your doctor anyway though, becasue I don’t know your history.

    Please also do this is you are HIV negative and using T:D as prevention.

  6. Samuel

    Am on TLD for 2 weeks now, but I have been coughing plus flu symptoms and a blocked nose since i start dem.

    Kindly help :)

  7. Josh Peasegood

    Hi Moyo, as these symptoms are all over your mums body she should speak to her doctor. How long has she had these symptoms for?

  8. Moyo

    Hi, any remedy for skin reaction when taking tld, it’s been two months taking them and my mummy has developed some genital warts some rashes on almost every part of the body

  9. Josh Peasegood

    Hi Tracy, yes you can change the time for your medication. Please see here for information regarding changing skin colour: https://i-base.info/qa/803

  10. Tracy

    Hi…I’ve been taking tld 7am but I feel its too early…is it okay to change the time? also I have been noticing dark spots on my arms and legs…is there a remedy for this?

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