Q and A

Question

I have a serious rash from starting treatment – should I stop taking my meds?

I am a 30 year old woman I got tested for HIV in 2009 and was found positive. In April 2010 I developed Kaposi’s Sarcoma but had only a few lesions. In December 2010 my CD4 count was 221 and I started ARVs, within a week I developed a very bad rash and they had to change my medication, I had been on this new drug for two weeks and I developed another rash which gets worse every day and I’m seriously considering stopping taking ARVs altogether because I feel like I was healthier without them and the rash is really affecting me, physically and emotionally. Please advice

Answer

Thank you for your question. I am sorry to hear you are having such a hard time taking the HIV medication. Many people experience side effects when starting medication. Some of these side effects lessen 2-4 weeks after starting the meds. If they continue then you should talk to your HIV doctor about changing your meds again until you find the right combination for you. You should not stop taking the meds or you will become sick very quickly and you could end up with resistance to some of the meds. This will limit your treatment choice in the future.

Although many drugs are linked to rash, the severity of rash and how long it lasts varies considerably. With some drugs, if you develop a rash during the first few weeks of therapy you must report this immediately to your doctor. This is because it can sometimes lead to very serious reactions. These drugs are abacavir (Ziagen, and in Trizivir and Kivexa), nevirapine (Viramune), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva) and T-20 (enfuvirtide, Fuzeon).

Other rashes are more likely to be mild and disappear without treatment, or can be easily treated with antihistamine drugs such as cetirizine (Zirtek) or loratadine (Clarityn).

It would help me give you a more specific answer if you could tell me the meds you took previously and the ones you are on now?

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104 comments

  1. Lisa Thorley

    Hi Dd,

    This could be a reaction to the medication. As you’ve got a rash you’ll need to let your doctor know.

  2. Dd

    Hi I started using tribuss 1 week ago, am developing a bad rash on my face, hands and black spot under my arms

  3. Lisa Thorley

    Hi Anonymous,

    Yes, it’s possible that this is a reaction to the meds. As it’s a rash you should see a doctor.

  4. Anonymous

    Hi

    Im 6 months pregnant and started taking trivenz for almost 2 weeks now. Ive developed a non- itchy rash on my thighs, chest and abdomen.

    Is this a side effect of the medication?

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