Q and A

Question

Can I take Tribuss with food?

Hi! I am 35 years and started taking my tribuss pill in February 2012. My problem is that I cant take the pill on an empty stomach. Can this make the pill to disfunction?

Answer

Hi,

Thank-you for your question.

Tribuss is a generic combination treatment which contains three HIV drugs. These are efavirenz, FTC and tenofovir. In the UK, this combination in a single pill is called Atripla.

Tribuss is usually recommended to be taken on an empty stomach is to reduce side effects. This is up to 60% more efavirenz is absorbed if it is taken with a high fat meal.

This would mean there is more efavirenz than you need and you may be more likely to get side effects. Side effects from efavirenz include dizziness, mood changes and sleep disturbance. Please follow this link for more information about efavirenz side effects.

However, the increased levels of efavirenz are connected to a high fat meal.

If you prefer to take Tribuss with some food this is fine, just not with fatty foods.

Please let me know if you have any more questions!

324 comments

  1. Lisa Thorley

    Hi Tsekiso,

    It sounds like you need to see a doctor. This is because headaches and itchy eyes can be caused by numerous things.

  2. Tsekiso

    Hi Lisa,I have been taking tribuss since 2012 and lately I have been having terrible headache,itchy eyes(feel like sleeping) and sleeping a lot.

  3. Lisa Thorley

    Hi Boniswa,

    i-base advocates are not medical doctors. Therefore, you should visit your doctor and ask them what the black dots are.

  4. boniswa

    I started taking Tribuss early January, I’m now having some black dots all over my body, so what must I do???

  5. Lisa Thorley

    Hi Sbo,

    All the meds that you’ve been taking are generic versions of Atripla. Therefore, there shouldn’t be any change in how your body copes. However, it can happen that you’ll have some side effects when changing.

    Because you’re so unwell, I would advise that you go and speak to your doctor. It could be the Tribuss that is doing this, or something very different.

  6. Sbo

    Hi Lisa , i started my meds June 2016 at first i was given Atrioza which i never had problem with it . After 2 months i was changed to Odimune. In November was changed to Tribuss at first month never had a problem. It started in mid Jan. Now I’m scared of ulcers cause this cramps are very painful and unbearable. Now its runny stomach. I’m even scared of meals because once I eat something my stomach burns. Please help I am loosing weight now. Even if drink water this cramps worry me.

  7. Lisa Thorley

    Hi Sbo,

    How long have you been on Tribuss for? If you’re new to it, then this is a common side effect. It can be helped by asking your doctor for some anti-diarrhea medication. If this doesn’t work, then you may need to change meds.

  8. Sbo

    Hi I’m on Tribuss and lately I’m experiencing some terrible stomach cramps. Every morning I pass loose stools like diarrhoea. Do you think I should change the medication or I must I get something to detox?

  9. Lisa Thorley

    Hi Brighty B.

    Viral load blips can and do happen. This is even if you adhere to your medication. Please see here for more info:

    http://i-base.info/guides/changing/viral-load-blips

    If it’s possible to have your viral load retested, then this is something you could do.

  10. BRIGHTY B

    hi, am 32yr old I recently visited the doctor and he told me my viral load was previously 29 now 225 but I have been taking the treatment as prescribed by them. what does it mean? Is there a problem?

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