Q and A

Question

Is there a difference between Atripla, Odimune, Rizene and Tribuss etc

Hi

I started with Atripla, then received Odimune and now I have been given Tribuss from my provider.

I have never had side effects. How safe is it for me to take Tribuss?

I’m afraid it might change how I look. Is it the same as the two I have already been taking?

Answer

Hi

Tribuss and Odimune are generic versions of the fixed dose combination pill Atripla. These drugs have different names because they are made by different manufacturers.

Each version contains the same doses of three drugs. These are tenofovir, FTC and efavirenz.

There are no safety concerns from switching from one version to another.

Although some HIV meds have been linked to body shape changes, this is not commonly reported for any of these drugs. One exception, generally rare, is that efavirenz has been linked to weight gain in breast tissue – also called gynaecomastia (GYE-na-co-MAS-tee-ah).

See:

Efavirenz-associated gynaecomastia reported to the national HIV and TB healthcare workers hotline in South Africa

Dihydrotestosterone for HAART-associated breast enlargement in men

This answer was updated on 12 July 2020 from an original question on 21 May 2013.

134 comments

  1. Simon Collins

    Hi Sthembile

    Changing from evening to morning doses should not have may the viral load increase. In the UK these meds are not recommended if you do shift work because or the difficulty adjusting doses.

    How high is your viral load now?

    It would be good to repeat the test if you can do this.

    What has your doctor said? It might be easier to use a different combination if the shift work is difficult, even if your viral load goes back down again.

  2. sthembile

    I have been on Tribuss and changed to Odimune but now I’m working straight night shift and I’ve changed the time I take my medication to mornings because I sleep during the day and my last check up my viral load had escalated,could it be because I take my meds in the morning?

  3. Simon Collins

    These are all the same drugs – only the labels are different.

  4. ayanda

    Hi, between atripla, atroiza and tribuss which one changes the shape of a person?? Like small legs and bigger upper body??

  5. Simon Collins

    Hi Lydia

    All these meds are the same drugs – just made by different manufacturerer.

    Generic versions of Atripla include Atenef, Atroiza, Citenvir, Odimune, Tribuss, Trivenz, Truno, Trustiva and Viraday. These meds have contain the same active ingredients as Atripla and are just as safe and effective. Tenarenz and Eflaten are generic versions that are similar but contain 3TC instead of FTC.
    http://i-base.info/guides/1561

    This means there should not be any difference in how effective they are or in how you tolerate treatment.

  6. Lydia

    I started treatment last yr September they gave me atroiza,then they changed to odimune. At the clinic they just change they don’t explain why do they change. Yesterday I went to the clinic again they changed to Atenef and i will start it maybe next week after finishing Odimune.I want to know if there are the same bcs Odimune was very good I didn’t have side effect. Pls help me.

  7. Robin Jakob

    Hi,

    You should not get any new side effects. This is because Tribuss and Atroiza are both generic versions (copies) of a pill called Atripla. This means they contain the same ingredients and work in the same way. They only have different names because they are made by different companies.

  8. nontobeko

    I started to use Tribuss few weeks ago i never had any side effects beside dizziness for few minites, now they gave me Atroiza. Am i going to have side effects?

  9. Robin Jakob

    Hi,

    Atroiza and Tribuss are both generic versions (copies) of a pill called Atripla. They all work in the same way and contain the same three medications. They only have different names because they are made by different companies.

    You can find more information about the drug here:
    http://i-base.info/guides/1561

  10. botlhale

    I have been using atroiiza for 6months now I did get tribuss how dangerous it is to change medication or am I going to get side effects again

Comment

Your email address will not be published. Required fields are marked *