Q and A

Question

Is there a difference between Atripla, Odimune, Rizene and Tribuss etc

Hi

I started with Atripla, then received Odimune and now I have been given Tribuss from my provider.

I have never had side effects. How safe is it for me to take Tribuss?

I’m afraid it might change how I look. Is it the same as the two I have already been taking?

Answer

Hi

Tribuss and Odimune are generic versions of the fixed dose combination pill Atripla. These drugs have different names because they are made by different manufacturers.

Each version contains the same doses of three drugs. These are tenofovir, FTC and efavirenz.

There are no safety concerns from switching from one version to another.

Although some HIV meds have been linked to body shape changes, this is not commonly reported for any of these drugs. One exception, generally rare, is that efavirenz has been linked to weight gain in breast tissue – also called gynaecomastia (GYE-na-co-MAS-tee-ah).

See:

Efavirenz-associated gynaecomastia reported to the national HIV and TB healthcare workers hotline in South Africa

Dihydrotestosterone for HAART-associated breast enlargement in men

This answer was updated on 12 July 2020 from an original question on 21 May 2013.

134 comments

  1. Lisa Thorley

    Hi Busi,

    Odimune and Tribuss are both generic versions of Atripla. What this means is that they contain the same compounds. It not common to have side effects when taking different generic forms of Atripla, it can however happen. Can you ask to be given just Tribuss?

  2. Busi

    Odimune makes me vomit all the time but with tribus I’m always fine

  3. Lisa Thorley

    Hi Vinci,

    Odimune and Hheftenam are both generic versions of Atripla, please see here:

    http://i-base.info/guides/1561

    What this means is that they contain the same compounds. Therefore, its fine to switch.

  4. Vinci

    Hi I’ve being using Odimune now the doctor gave me Heftenam, is this OK?

  5. Lisa Thorley

    Hi Budrall,

    i-base are an organisation that work for and with people who are positive. Therefore, this isn’t something that we can help you with.

  6. Budrall

    I hereby would like to find out what could be going on. My wife am married for 4 years nw and have 2 boys with. I have discovered used containers of Odimune and Atroiza in the babies draws. And sometime back when I asked her she denied saying, they are Tablets she collects on behalf of someone else. And since then she has been hiding them…Therefore, recently I found them and started to monitor the situation and she has been taking them. Every day am checking from 28 Tablets now they are only 13 remaining in one container. Am really Worried and I dont know how to approach her. Seemingly, something is not ryt.. We just a new born who is 4 months now and also discovered the presence of Cipla Nevirapine in the bby’s Chest drawer. By the way my wife is a Register Nurse. Please can some one advise what could be going on here.
    Hope to hear from you soon.

    Regards

  7. Lisa Thorley

    Hi Lungile,

    Atrozia is a generic version of Atripla. What this means is that it contains the same compounds as Atripla. In effect they are the same drug, just with a different name and shape. For more info, please see here:

    http://i-base.info/guides/1561

  8. Lungile

    I’m usually given Atrozia, now I’ve been given Atripla, is this OK?

  9. Lisa Thorley

    Hi Getty,

    The following link discusses fat loss. And what can possible be done.

    http://i-base.info/guides/side/lipodystrophy

  10. Getty

    Hi
    I have been using Nevarapine and Lamzid for years which was good to me but was changed to Trivenz around 2011. But i have noticed the loss of fats in my legs and found out that according to studies it causes a lack of fats in the leg. Which medication can I change to that can reverse the loss of fats?

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