Q and A

Question

Is there a difference between Atripla, Odimune, Rizene and Tribuss etc

Hi

I started with Atripla, then received Odimune and now I have been given Tribuss from my provider.

I have never had side effects. How safe is it for me to take Tribuss?

I’m afraid it might change how I look. Is it the same as the two I have already been taking?

Answer

Hi

Tribuss and Odimune are generic versions of the fixed dose combination pill Atripla. These drugs have different names because they are made by different manufacturers.

Each version contains the same doses of three drugs. These are tenofovir, FTC and efavirenz.

There are no safety concerns from switching from one version to another.

Although some HIV meds have been linked to body shape changes, this is not commonly reported for any of these drugs. One exception, generally rare, is that efavirenz has been linked to weight gain in breast tissue – also called gynaecomastia (GYE-na-co-MAS-tee-ah).

See:

Efavirenz-associated gynaecomastia reported to the national HIV and TB healthcare workers hotline in South Africa

Dihydrotestosterone for HAART-associated breast enlargement in men

This answer was updated on 12 July 2020 from an original question on 21 May 2013.

134 comments

  1. Lisa Thorley

    Hi Snami,

    Atrozia and Odimune are both generic versions of Atripla. What this means is that they contain the same compounds. It’s common to switch between the generic versions. Please see here: http://i-base.info/guides/1561

  2. Snami

    I must started with atroiza and now given odimune I scare maybe it change my life

  3. Roy Trevelion

    Hi Tsholo,

    Atripla and Trivenz contain the same drugs. These drugs have different names because they are made by different manufacturers.

    Please see this link for more brand names for Atripla.

  4. tsholo

    What is the difference between Atripla and Trivenz?

  5. Lisa Thorley

    Hi Thobisa,

    How long have you been taking the Odimune? Are you taking it as prescribed? See here for more info for how and when it should be taken: http://i-base.info/guides/1561

  6. Thobisa

    Hey i stared with acriptega now they give me odimune after taking odimune i feel so drunk when i wakeup now in my left head i feel so cold

  7. Lisa Thorley

    Hi Thembi,

    Atrozia and Odiumune are both generic versions of Atripla, please see here: http://i-base.info/guides/1561 What this means is that they contain the same compounds. It’s common to switch between the different generic versions.

  8. Thembi

    I’ve started with atroiza now I have been given odimune must I be scared

  9. Roy Trevelion

    Hi Thulan,

    Tribuss and Atroiza are generic versions of Atripla. So the tablets contain the same active meds. But they are from different manufacturers.

    There are no safety concerns from switching from one to the other.

  10. Thulan

    I have just started arv’s ,at first they gave me tribuss after 28 days then i was given atroiza can i use it

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