26 August 2010

Contents

Editorial

• Volume 11 Number 7/8 July/August2010

Conference reports

• XVIII International AIDS Conference: 18-–23 July 2010, Vienna

• Navigating the IAS Vienna conference online

• Results from the Caprisa 004 tenofovir microbicide trial

• Quadrivalent HPV vaccine reduces genital lesions and HPV acquisition in men

• Rilpivirine (TMC-278) vs efavirenz in treatment-naive patients: phase 3 results

• Once-daily nevirapine extended release (XR) is non-inferior to current formulation

• GSK572 (dolutegravir): second-generation integrase inhibitor

• TBR-652: early results for CCR5 inhibitor

• Atazanavir/r plus maraviroc or tenofovir/FTC in treatment-naive patients

• Unboosted twice-daily atazanavir plus raltegravir

• CASCADE analysis of when to start treatment

• Impact of antiretroviral PMTCT prophylaxis regimens on subsequent maternal disease progression in Kesho Bora

• Birth outcomes with antiretroviral exposure

• New WHO guidelines for children (July 2010)

• Early treatment for infants is cost-effective

• No difference in outcomes for children initiating treatment with a protease inhibitor or an NNRTI nor with viral load switching strategies in PENPACT-1

• Tablets more acceptable than syrups in the ARROW trial

• Paediatric formulation of TMC 278

• Smoking and atazanavir levels

• Darunavir/ritonavir and rosuvastatin

• Lime juice is not a microbicide: do not try at home

Antiretrovirals

• FDA safety updates to antiretroviral labels

• Raltegravir approved inScotland

• Atazanavir/r approved in Europefor children aged 6 to 18 years

• FDA finally approves 4th generation HIV Ag/Ab test in the US

Treatment access

• FDA approval of generic ARVs

Pregnancy

• Potential impact of new WHO pregnancy guidance (2010)

• Access to formula milk for HIV-positive mothers in the UK

PK and drug interactions

• Darunavir/ritonavir and hepatic impairment

• Case report – lack of PK interaction between bosentan and nevirapine

• Pharmacokinetics of once daily darunavir/ritonavir and efavirenz

Basic science and immunology

• HIV infection, inflammation and premature ageing

• Antiretroviral therapy dramatically reduces HIV transmission

On the web

• Conference reports and online abstracts

• Reports and journals

• Community resources and publications

• Medical resources