October 2017

Contents

Editorial

• September/October 2017: Volume 18 Number 9/10

• New guides to PrEP

Special reports

• Experts disagree with controversial BMJ support for older HIV drugs in pregnancy

• The evidence for U=U (Undetectable = Untransmittable): why negligible risk is zero risk

Conference reports

• 9th IAS Conference on HIV Science (IAS 2017)

• Dual therapy with darunavir/r plus lamivudine as first-line ART

• Dual therapy with dolutegravir plus lamivudine as first-line ART

• Once-daily raltegravir: 96-week results from the ONCEMRK study

• New IPERGAY analysis shows on-demand PrEP dosing works with less frequent sex

• On-demand dosing for PrEP is highly effective in French expanded access programme

• Psychological impact of PrEP: beyond efficacy and cost-effectiveness

• Early ART and testing HIV negative with rapid HIV tests

• Report from the IAS HIV Cure & Cancer Forum, 22–23 July 2017, Paris

Antiretrovirals

• Gilead uses voucher to speed FDA review of bictegravir

Treatment access

• Generic dolutegravir-based FDCs at US $75 a year for low- and middle-income countries

• UK donates well to the Global Fund, but slashed bilateral aid for HIV

• Dozens of countries left out of new PEPFAR strategy, threatening the global AIDS response

• NHS access to PrEP in the UK: country update

• Generic PrEP in France and Scotland challenges access across the UK

Pregnancy

• BHIVA challenges BMJ recommendations on ART during pregnancy: tenofovir still strongly recommend

Guidelines

• UK PrEP guidelines: online for comment (Oct 2017)

• US IDSA HIV pain management guidelines (2017)

Side effects

• Increased frequency and progression of kidney disease in HIV positive people

Coinfections and complications

• Enhanced OI prophylaxis reduces mortality when starting ART late

HIV prevention and transmission

• PrEP use in adolescent gay and bisexual men: US study shows need for easier access and easier PrEP

Other news

• STOPAIDS reviews DFID’s work on HIV and AIDS

On the web

• HIV and drug adherence: RITA!

PDFs

• September/October 2017: Volume 18 Number 9/10