HTB homepage • Conference reports • Articles by subject • Subscribe February 2018 Contents Editorial 23 February 2018: vol 19 no 4 09 February 2018: vol 19 no 3 Conference reports CROI 2018 – highlights from the preliminary programme Antiretrovirals FDA grants tentative approval to first DTG/FTC/TAF FDC Bictegravir approved in the US in new integrase-inhibitor based FDC (Biktarvy) US approve a lower-dose efavirenz (400 mg) based generic FDC (Simfi Lo) ViiV announces phase 3 study switching to dolutegravir/3TC dual therapy from TAF-containing ART US darunavir label updated: drug interactions and pregnancy Treatment access Universal ART on diagnosis: approved by NHS England 75% of WHO essential medicines could be cheaper: UK and South Africa both overpay London clinic to prescribe generic PrEP privately at £55 for 30 tablets Pregnancy Standard once-daily dolutegravir dosing achieves target levels during pregnancy New HIV pregnancy study uses latest ART: IMPAACT 2010 study (VESTED) includes dolutegravir and tenofovir alafenamide (TAF) Association between timing of maternal ART and risk of infants born small for gestational age in Dutch ATHENA cohort PK and drug interactions Significant drug-drug interaction between dolutegravir and isoniazid-rifapentine Guidelines BHIVA standards of HIV care (2018): online for comment UK HIV pregnancy guidelines (2018): online for comment Side effects Meta-analysis reports no significant risk of cardiac, IRIS or suicide with dolutegravir Cure-related research New data on identifying and targeting the latent HIV reservoir Recruiting natural killer cells to target HIV persistence Other news Discrimination against gay men overturned with new HPV vaccine programme for England UK study highlights discrimination against trans people living with HIV On the web PrEP resources for access HIV conversations in the UK Women in Science: IAS feature Yale CRIT conference: blogs on the threats from changes to drug regulation in the US and Europe PDFs 23 February 2018: vol 19 no 4 09 February 2018: vol 19 no 3 HTB homepage • Conference reports • Articles by subject • Subscribe
