March 2018

Contents

Editorial

• 30 March 2018: vol 19 no 6 – CROI 2018 part 2

• 14 March 2018: vol 19 no 5 – CROI 2018 part 1

Conference reports

• CROI 2018: second reports

• Ibalizumab 24-week phase 3 results and susceptibility to drug-resistant HIV

• Statin use might reduce risk of cancer in HIV positive people

• Rate of bone loss on ART slows after the first year

• Standard dose of dolutegravir sufficient in late pregnancy: interim results from DolPHIN-1 study

• Women’s risk of becoming HIV positive increases three-fold in late pregnancy and four-fold postpartum

• Cure research at CROI 2018: defining and reducing the reservoir and the risks from interrupting treatment

• 25th Conference on Retroviruses and Opportunistic Infections (CROI 2018)

• Inching towards an HIV cure: bNAb and TLR-7 agonist reduce viral rebound off-ART in macaques

• No HIV evolution in plasma or lymph nodes on suppressive ART and no impact from further intensification

• Dual therapy can reduce TB prophylaxis from nine months to one: fewer side effects and more people complete treatment

• Twice-daily dolutegravir is effective and tolerable with rifampicin 

• Once-daily tenofovir alafenamide appears sufficient when dosed with rifampicin

• Efavirenz 400 mg can be given with anti-tuberculosis treatment 

• Bictegravir at CROI 2018: switching studies and drug resistance analyses

• PrEP at CROI 2018 (part 1): Access in Australia and the US

• PrEP at CROI 2018 (part 2): Animal studies for future drugs

• BHIVA best of CROI feedback workshops

Antiretrovirals

• FDA approves ibalizumab in the US to treat multidrug HIV resistance

HIV prevention and transmission

• Update on PrEP IMPACT study (March 2018)

Cure-related research

• Elite controllers: sex differences and factors associated with loss of immune control

• Assessing antiretroviral therapy interruptions in HIV cure research

Other news

• US Congress rejects Trump’s proposed cuts to research budget for 2018

On the web

• HCV advocacy training manual

PDFs

• 30 March 2018: vol 19 no 6

• 14 March 2018: vol 19 no 5