December 2012

Contents

Editorial

• Volume 13 Number 11/12 November/December 2012

Conference reports

• 11th International Congress on Drug Therapy in HIV, 11-15 November 2012, Glasgow

• Issues that divide expert opinion: when to start, HIV and ageing and the impact of HIV on life expectancy

• Dolutegravir: integrase resistance and the impact of the background regimen

• Updated results on Quad: 96 week data from phase 3 studies

• HIV/HCV coinfection: early glimpses of an interferon-free future and EuroSIDA incidence data

• Resistance in infants and children receiving ART in South Africa

• 63rd Annual Meeting of the American Association for the Study of Liver Disease (AASLD), 9-13 November 2012, Boston

• Cure rates with pipeline HCV drugs: reports from AASLD

• 3rd International Workshop on HIV and ageing, 5-6 November 2012, Baltimore

• BHIVA Autumn Conference, 6-7 October 2012, London

Antiretrovirals

• Darunavir 800 mg tablet approved in the US

Treatment access

• FDA approval of generic ARVs

• d4T – time to move on

• Global Fund provides ART for 4.2 million people: 2012 update

• $84 million grant to Zimbabwe to reach universal access in 2012

• Mark Dybul to be the next executive director of the Global Fund

• US NIH to enforce open access to clincal trial results

Pregnancy

• The challenge of adherence during pregnancy and after

Paediatric care

• ART and adverse birth outcomes in Botswana

Guidelines

• UK Standards for HIV Care launched by BHIVA (2012)

Side effects

• Low incidence of liver-related deaths in HIV positive people without HBV and/or HCV co-infection

• Rapid drop in mitochondria in fat biopsies within four weeks of d4T use

• High dose multivitamin use in advanced HIV has no benefit to CD4 and viral load and may cause liver toxicity

HIV prevention and transmission

• Quantifying HIV-1 exposure to illuminate resistance to infection

• Immune activation, inflammation and HIV acquisition risk

Cure-related research

• Hopes raised by HDAC inhibitor, but uncertainties remain

• Post-treatment control of HIV replication and prospects for a functional cure

Book and film reviews

• Bad Pharma: How drug companies mislead doctors and harm patients: by Ben Goldacre

Other news

• HIV in the United Kingdom: 2012 report

• Hepatitis C in the UK: 2012 report

• New Frontiers: Inaugural meeting of the British Society for Nanomedicine

• Anti-homosexuality laws back in African parliaments

PDFs

• Volume 13 Number 11/12 November/December 2012 PDF