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Pipeline reports: i-Base/TAG annual reviews (2010 – 2016)

NOTE: For later pipeline reports produced as the i-Base Fit For Purpose publications please see: https://i-base.info/hiv-pipeline-reports-2010-2019 From 2010 – 2016,  i-Base collaborated with Treatment Action Group (TAG) to produce an annual review of latest research. Since 2017, i-Base produce separate …

Preguntas y Respuestas sobre el estudio PARTNER: Cómo interpretar el resultado de cero transmisiones

El siguiente cuestionario está relacionado con el estudio PARTNER que fue publicado en la edición del 12 de julio de 2016 de Journal of the American Medical Association (JAMA), cuya versión completa está disponible de forma gratuita. A continuación se …

Q&A on the PARTNER study: how to interpret the zero transmission results

Full paper published in JAMA as open access article.

Pipeline report 2016

Annual overview of HIV and TB pipeline research: paediatrics and adults

Open letter: on futility of proposed UK PrEP study

The following letter was sent to Public Health England (PHE) in response to being asked to join a community advisory board for proposed further PrEP research. There are important questions about PrEP but this proposed study is looking at none …

Two PrEP crowdfunders – UK help needed today…

One of the most significant and healthy changes over the last year has been the new energy and activism over HIV prevention work – and for the UK this is particularly notable.  Much of this has been focused on PrEP …

May/June HTB now online

NHS decision to block PrEP, reports from BHIVA, EASL, CROI and HIV and Women conferences, use of HPV vaccine – and remembering i-Base founder Paul Blanchard…

A simple ask in 2016: the UN goal of universal HIV treatment

This post is about two open meetings I attended this month at the United Nations as part of preparations for the upcoming UN High Level Meeting on HIV/AIDS in June 2016. These meetings were for community input into the next …

Legal threat causes NHS England to rethink PrEP access to prevent HIV

Optimistic news suggests that UK access to PrEP may still be considerd in June, following a threat of legal action against NHS England for their decision terminate public discussion on a stakeholder report that had recommended approval. On 19 April …

Activists convince Washington Post that Pfizer lowers prices: global action highlights fairer alternatives – this story has been removed!

Simon Collins, HIV i-Base The dominant market structure where pharmaceutical drug pricing blocks access to otherwise cheap-to-manufacture life-saving medicines from the people who most need them, was highlighted by international activists on Friday. This was a coordinated action linking community-based …

Activists convince Washington Post that Pfizer lowers prices: global action highlights fairer alternatives – this story has been removed!

The dominant market structure where pharmaceutical drug pricing blocks access to otherwise cheap-to-manufacture life-saving medicines from the people who most need them, was highlighted by international activists on Friday. This was a coordinated action linking community-based organisations from seven countries …

Sign-on for PrEP to be raised in Parliament

Sign on now… Approved in the US, France, Canada and South Africa. Public discussion banned by NHS England… access blocked in UK

March/April HTB now online

Dozens of studies from CROI 2016: PrEP, new HIV drugs, paediatric and access… plus STOP-PRESS news that NHS England blocks PrEP in the UK…

CROI 2016 – first reports: PrEP, new HIV drugs, cure and access

First reports from CROI in Boston: dozens of studies and an overview of other issues…

January/February HTB now online

Access to care in the UK, generic dolutegravir at $44 per year, new US and WHO guidelines, PrEP submited for EU approval…

Immune reconstitution inflammatory syndrome

Immune reconstitution inflammatory syndrome – see: IRIS

life cycle

life cyle – the steps for an organism to reproduce or replicate. The HIV life cycle includes: Attachment and binding to a CD4 cell). Fusion or joining the cell. Reverse transcription. When the single strand RNA becomes a double strand …

antepartum

antepartum refers to the time during pregnancy before a baby is born. Antepartum refers to the mother. See: intrapartum and postpartum.

postpartum

postpartum refers to the time after a baby is born. Postpartum refers to the mother. See: antepartum and intrapartum.

formulation

formulation – the physical form that makes an active drug into a medicine. Different formulations include Pills (capsules or tablets). Syrups or other oral solutions. Injections. Powders. Creams or lotions. A co-formulation is when two active drugs are combined. For example: when …

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