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We are asking readers to help us by completing a short online survey about HIV Treatment Bulletin (HTB) and other i-Base services: http://www.surveymonkey.com/s/8QQLN6X Your feedback is really important to us. Please take a few minutes to help us understand how …

This new and updated treatment guide includes information about changing treatment. The main focus is on treatment failure because of drug resistance. This booklet will help explain: Why your treatment failed. Which tests you need and what the results mean. …

It is with great regret, sadness and anger that we report that David Kato, a prominent Ugandan human rights activist, was murdered in his home in Kampala yesterday. A vigil is being organised at 11am on Friday 28th January outside …

The English edition of this bulletin on Antiretroviral Treatment for Intravenous Drug Users is now online and available as a PDF download. The Russian language edition will be distributed within two weeks. ARV4IDU is funded by the Open Society Institute. …

phenotype — relating to how an organism behaves, based on how its genotype relates to the environment. Phenotypic resistance tests look at whether HIV continues to grow in a test tube after increasing concentrations of a drug are added. See …

The first issue of HTB Turkey (HIV Tedavi Bülteni – Türkiye), a new Turkish-language information periodical has been produced by an independent group of Turkish doctors, activists and health care workers. HTB Türkiye.1 2010 PDF (2MB) Based on the i-Base …

i-Base been contacted by lots of people about the case of the man who had stem cells transplant who has now been off treatment for over three years without his viral load rebounding. It is very likely that if HIV …

Results from a safety study on the risks of using Bio-Alcamid to treat HIV-related facial fat loss (lipoatrophy) were presented at the 12th International Workshop on Adverse Drug Reactions and Co-Morbidities in London earlier this month. Researchers collected long term …

Fully updated and newly referenced guide.

virion – the name for a virus when it is not inside a cell, for example when new viral material leaves a CD4 cell and is floating in blood or plasma

dyspnoea – medical term for symptoms related to difficulty breathing, shortness or breath.

The following resources are developed for the introduction course.

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viral rebound – when your viral load has been undetectable (under 50 copies/mL) and then becomes detectable. Sometimes viral rebound can be a lab error, sometimes a small temporary blip, and sometimes a real rebound that shows your virus may …

randomise – in research, this is a way of decide at random which participants join each group. So neither you or your doctor chose which group you join in a research study. A common example is that the decision would …

point of care – referring to you doctors office (or wherever you access care)

Stevens-Johnson Syndrome – a type of severe rash that is luckily rare. This rash has been reported in 0.1–0.3% of people using NNRTIs. It can also occur with other drugs including antibiotics (including cotrimoxazole/Septrin). Any rash on an NNRTI should …

nanotechnology – science working with tiny particles at the level of manipulating individual molecules. This is an exciting field of medicine. Drugs developed with nanotechnology would need much lower drug doses (hopefully cheaper and having fewer side effects) and would …

microbicide – a gel that may protect against infection.In reference to HIV, this is usually referring to a gel that could be applied before sex. In 2010 a study called Caprisa 004 provided the first evidence that a microbicide (in …

late breaker – in research, this is a study presented at a medical meeting that was submitted to the conference organisers after the main programme had been decided. There are usually only a few dozen late-breakers, where the last minute …