June 2017

Contents

Editorial

• May/June 2017: Volume 18 Number 5/6

Treatment alerts

• Unexpected side effects with generic abacavir – and potential for rare reactions to other generic ARVs

Supplements

• ART in pictures: HIV treatment explained (June 2017)

Conference reports

• 18th International Workshop on Clinical Pharmacology of Antiviral Therapy, 14-16 June 2017, Chicago

• Dolutegravir pharmacokinetics in pregnancy

• High rates of of undocumented efavirenz-related side effects in Uganda

• 11th INTEREST Workshop, 16-19 May 2017, Lilongwe, Malawi

• Increased risk of ART failure after low-level viraemia in a large South African cohort

• Option B+ Malawi

• 24th Conference on Retroviruses and Opportunistic Infections (CROI 2017), 13-16 February 2017, Seattle

• Impressive HIV pipeline at CROI 2017

• Paediatric HIV: CROI 2017

Antiretrovirals

• Dolutegravir/rilpivirine submitted to EMA and FDA as oral two-drug maintenance combination

• Bictegravir/FTC/TAF: new once-daily integrase-based FDC submitted to US FDA

• FDA updates cobicistat and Stribild labels: interactions with systemic, inhaled, nasal and ophthalmic corticosteriods

Treatment access

• WHO adds dolutegravir and PrEP to updated Essential Medicine List

• Cochrane review of HCV treatment misses real issues of access to care

Paediatric care

• FDA approves sofosbuvir/ledipasvir and sofosbuvir for children aged 12 to 17

Side effects

• Case report of capsulitis with elvitegravir and cobicistat (EVG/c)

Coinfections and complications

• Increased prevalence of diabetes in HIV positive people

• Poppers and cancer risk in HIV negative and HIV positive gay men

HIV prevention and transmission

• HIV superinfection is associated with specific HLA types

• New study of combined HIV prevention and contraception ring

• Online video: PrEP 17 – The coming of age of PrEP

Cure-related research

• Evidence of smaller HIV reservoirs in a Ugandan cohort

Basic science and immunology

• Natural history of elite controllers

Other news

• King’s Fund report on HIV services in England

• Toolkit to support doctors against immigration interventions in the NHS

On the web

• Hepatology – a clinical textbook (8th edition, 2017)

• Hepatology – a clinical textbook (8th edition, 2017)

• Online video: PrEP 17 – The coming of age of PrEP

• HIV.gov – AIDS.gov relaunched

PDFs

• May/June 2017: Volume 18 Number 5/6