July 2022

Contents

Editorial

• HTB July 2022 (1 July 2022) now online

• Introduction to ART: i-Base guide (June 2022)

Special reports

• Monkeypox crisis in the UK needs urgent funding: sex, vaccines and Pride

Conference reports

• 29th Conference on Retroviruses and Opportunistic Infections (CROI 2022): final report

• CROI 2022: NAMSAL study comparing DTG to EFV400 in Cameroon: week 192 results

Antiretrovirals

• Lenacapavir gets positive opinion for approval in the EU to treat MDR HIV

• Combination bNAb’s sustain viral suppression for 40 weeks: phase 1 results

Paediatric care

• Dual bNAbs in children: dose-finding and safety data on VRC01LS and 10-1074 in the Tatelo study 

Side effects

• INSTIs and cardiovascular events in the RESPOND cohort: early increase at six months normalises after two years

mpox (monkeypox)

• UK offers limited vaccine to gay and bisexual men at risk of monkeypox: full dose offered in NYC

Coinfections and complications

• Gonorrhoea vaccine might halve infections and help combat drug resistance

• COVID update: new waves of BA.4 and BA.5 in the UK – all omicron variants linked to reduced antibody responses to vaccines

• Importance of booster vaccine to protect against emergent COVID-19 variants

• Similar COVID-19 vaccination responses in HIV positive people on ART and with good CD4 counts compared to HIV negative controls

• US study reports higher rates of breakthrough COVID in HIV positive vs negative controls

• BMJ reports UK government failed to protect doctors during COVID-19

Cancer and HIV

• Full results from ANCHOR study published in NEJM

HIV prevention and transmission

• Fantastic voyage: tracking adherence sensors in PrEP meds

Other news

• UK increases funding to UNAIDS: still dramatically lower than before last years’ 80% cut

PDFs

• HTB: no. 7 (1 July 2022) PDF downloads