March 2022

Contents

Editorial

• HTB March 2022 (1 March 2022)

• EACS statement on the war in Ukraine

• Organisations to support the crisis in Ukraine

Conference reports

• 29th Conference on Retroviruses on Opportunistic Infections (CROI 2022): First reports

• CROI 2022: Biktarvy (B/F/TAF): 5-year follow-up in two phase 3 studies

• CROI 2022: Injectable CAB/RPV-LA results after three years follow-up

• CROI 2022: Lenacapavir: 54 week results in treatment-naive participants of CALIBRATE study

• CROI 2022: Lenacapavir in treatment-experienced participants, and as PrEP in macaques

• CROI 2022: Fourth potential stem cell HIV cure – in a US woman using donor cord cells

• CROI 2022: Strategies to suppress viral load off-ART with 3BNC117, 10-1074 and other bNAbs

• CROI 2022: Targetting reservoir with ART + bNAb 3BNC117 + romidepsin maintained undetectable viral load off-ART for 3.7 years in one case

• CROI 2022: Dual bNAb treatment maintains undetectable viral load off-ART in 44% of children in the Tatelo Study

• CROI 2022: AAV8-VRC07 vaccine generates new bNAb production in HIV positive people for up to three years

• CROI 2022: No impact from high-dose vitamin D3 on reducing the HIV viral reservoir

• CROI 2022: Higher maternal mortality and adverse birth outcomes among women with COVID-19 in Botswana

• CROI 2022: ANCHOR study reduces anal cancer by 57% and supports screening for people living with HIV

• CROI 2022: Other studies on anal cancer

• CROI 2022: Telomere shortening associated with TAF but not TDF in CHARTER study

• CROI 2022: Injectable PrEP: impressive results, new viral load monitoring – but price questions access

• CROI 2022: Long-acting doravirine implants as PrEP to prevent vaginal HIV transmission in mouse study

• CROI 2022: LEAP Workshop online: research into long-acting drugs

Coinfections and complications

• Timing of menopause: experiences of women in Swiss HIV Cohort

Other news

• Robert Carr Research Award: call for nominations

COVID-19: HIV and COVID-19 coinfection

• Long COVID may be more common in people living with HIV

COVID-19: vaccine research

• Efficacy of mRNA vaccines in people with HIV or solid transplant recipients

COVID-19: investigational drugs

• Major review finds little benefit of remdesivir in people hospitalised with COVID-19

COVID-19: long COVID

• Resources on Long COVID

COVID-19: transmission & prevention

• Melatonin does not protect against SARS-CoV-2

COVID-19: on the web

• WHO webinars: COVID-19 Global Research and Innovation Forum

PDFs

• HTB: no. 3 (1 March 2022) PDF downloads