HTB

Pregnancy

Atazanavir exposure in pregnancy

Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-positive pregnant women

US updates guidelines on use of ARVs during pregnancy (Dec 2007)

Perinatal transmission of HIV in England 2002-2005

Risk factors for in utero or intrapartum mother-to-child transmission in Thailand

Pregnancy shows a positive impact on HIV disease progression

African infants CCL3 gene copies influence perinatal HIV transmission in the absence of maternal nevirapine prophylaxis

Low rates of mother to child transmission in the DREAM and MTCT-Plus programmes

Very low transmission rates among breastfeeding women receiving ART

Use of pre-exposure prophylaxis (PrEP) by sero-different couples wanting to conceive a child

Increased incidence of miscarriage with efavirenz use

UK (BHIVA) pregnancy guidelines online for comment (2007)

Increased rates of pre-term delivery are associated with the Initiation of HAART during pregnancy: a single-centre cohort study

Antiretroviral therapy and premature delivery in the United Kingdom and Ireland

Early response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine

Mother to child transmission during exclusive breastfeeding

Surveillance of mother-to-child-transmission programmes: the case for universal screening

Rapid progression in infants infected with HIV despite single dose nevirapine prophylaxis

No benefit of early cessation of breastfeeding in the Zambia Exclusive Breastfeeding Study (ZEBS)

Role of infant feeding and HIV in a severe diarrhoea outbreak in Botswana

Diarrhoea in uninfected infants of HIV-positive mothers who stop breastfeeding at 6 Months

Post-weaning gastroenteritis and mortality in HIV-uninfected infants receiving antiretroviral prophylaxis

Rates of diarrhoea associated with early weaning among infants in the Kisumu breastfeeding study

Early breastfeeding cessation among infants and risk of serious gastroenteritis: findings from a perinatal prevention trial in Kampala, Uganda

Pregnancy outcomes in the DART trial

12 month response to HAART in women following exposure to prevention of mother to child transmission regimens

Response to nevirapine containing HAART following single dose nevirapine for PMTCT

US perinatal guidelines updated (2006)

Maternal health and prevention of mother to child transmission

18-month effectiveness of short-course perinatal antiretroviral regimens combined to infant-feeding interventions for PMTCT in DITRAME PLUS ANRS 1201/1202 2001-2005

HIV prevalence rates amongst 6 week old infants in South Africa: the case for universal screening at immunisation clinics

Maternal illness during pregnancy is associated with In utero mother to child transmission

Effect of pregnancy on PK of protease inhibitors

Pharmacokinetics of antiretrovirals in pregnancy: tenofovir, nelfinavir, lopinavir/r

Risk of central nervous system birth defects associated with ART exposure during pregnancy

No increase in adverse pregnancy outcomes in Thai women receiving nevirapine-containing HAART

Association of HIV replication capacity with mother to child transmission

Association between HIV subtype and detection of K103N

The effect of repeated single-dose nevirapine for PMTCT in a second pregnancy

Should criteria for initiation of HAART be revisited in pregnant women?

Cotrimoxazole prophylaxis in pregnancy

Pregnancy studies at EACS

US pregnancy guidelines updated (Dec 2005)

Breast milk, HIV suppression and decreased mother to child transmission

Single dose nevirapine infant prophylaxis to reduce mother to child transmission may have similar efficacy to maternal and infant doses

Benefits of adding 4 or 7 days of AZT/3TC to single-dose nevirapine to prevent MTCT: further analysis from TOPS

New drugs in pregnancy: atazanavir; T20

US Preventative Services Task Force recommends screening all pregnant women for HIV

Resistance during MTCT strategies: new data on protective benefit of Combivir added to single-dose nevirapine, and impact of treatment and breastfeeding on the infant

Use of T-20 in pregnancy: case study shows transmission occurred in highly treatment experienced mother with multiple-drug resistance

Further reading on nevirapine resistance

Long-awaited UK pregnancy guidelines now updated; pregnancy studies in Dublin

Developments in nevirapine use in MTCT reduction

Mashi study – late breakers on breastfeeding

Maternal health and infant mortality

Nevirapine associated adverse events in a cohort of pregnant women

Indinavir not recommended in pregnancy due to reduced pharmacokinetic levels

Study raises questions about cost effectiveness of nevirapine regimen

Low effectiveness of nevirapine to reduce MTCT in real life situation

Use of T-20 at the end of pregnancy to a multi-treated HIV-infected woman with virological breakthrough

MTCT programmes in South Africa: nevirapine and the minister

Adding Combivir to single dose nevirapine for reduction of MTCT significantly reduces resistance

Lopinavir/r levels reduced during pregnancy

Persistent nevirapine resistance following mother to child transmission interventions

Tipranavir resistance and viral response: L90M did not reduce response, recommendation to use with T-20

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