24 April 2017

Contents

Editorial

• March/April 2017: Volume 18 Number 3/4

Special reports

• i-Base appeal: we need your help…

Conference reports

• 23rd Annual Conference of BHIVA, 4-7 April 2017, Liverpool

• Drop in HIV incidence in gay men: frequent testing, early ART and PrEP

• Prompt/early ART: Dean Street pilot project reports 75% uptake

• Potential for phylogenetic analysis to show direction of HIV transmission

• Community presentations: dental care, HIV awareness and access to formula milk

• Initiatives for earlier HIV diagnosis: opt-out ER and home testing

• No new HIV cases in 398 people using PrEP at Dean Street clinic

• Other selections and webcasts

• 24th Conference on Retroviruses and Opportunistic Infections (CROI 2017), 13-16 February 2017, Seattle

• Dose reduction potential of nanoparticle ARV formulations confirmed in humans

• VRC01 in HIV-exposed newborns: first results support monthly injections for those at risk through breastfeeding

• Raltegravir pharmacokinetic targets met in high-risk HIV-exposed infants

• Tenofovir alafenamide exposure is modestly higher in children than adults

• New HIV diagnoses in children in UK and Ireland continue to decline

• World Health Organisation paediatric dosing tool

• Pre-ART drug resistance in rural South Africa but limited clinical impact with good adherence

• Immune-based therapy canakinumab reduces inflammatory markers in HIV positive people on ART

• Significant interaction between once-weekly isoniazid/rifapentine and daily dolutegravir: study stopped due to toxicity

• Increased risk of IRIS with integrase inhibitors reported in two studies

• Breakthrough for treating XDR-TB and ameliorating TB-IRIS

• PrEP in pregnancy does not increase poor birth outcomes

• HIV cure research and basic science: capsules from CROI 2017

Treatment access

• PrEP approved in Scotland but not in Wales

Guidelines

• EACS guidelines: seven translations now online (2017)

Cure-related research

• Flagging the HIV reservoir: a potential new marker for CD4 cells hiding HIV

Other news

• HIV: is victory in sight? – Brighton talk

• Introduction to cost-effectiveness analysis for infectious diseases

• Clinical management of HIV: EACS online course

On the web

• Community report: RITA: dyslipidemia with HIV