HTB

Side effects

Abacavir hypersensitivity reactions in patients who rechallenge after interruptions for reasons other than hypersensitivity

Prolonged CNS side-effects of efavirenz can be severe and lead to treatment discontinuation

Triglyceride increase can predict lipodystrophy in HIV patients under highly active antiretroviral therapy

Peripheral neuropathy: new data on risk factors, incidence and association with viral load

High prevalence of osteonecrosis of the hip found in HIV-infection

In switch study, women twice as likely as men to discontinue HAART due to toxicities

Neuropsychiatric complications of nevirapine treatment

Paracardial fat in HIV-infected patient resembles pericardial effusion

Altered adipocyte differentiation associated with protease inhibitors and lipoatrophy

High mortality rate in patients with severe NRTI-associated lactic acidosis

Tenofovir adversely affects development in foetal monkeys

Tenofovir not toxic to mitochondria in human cell culture

Study results shed light on cardiovascular risks: role of antiretrovirals and metabolism of lipids and sugars

Switch to abacavir improves lipoatrophy

Potential use of niacin to reduce intra-abdominal fat

Further benefits shown with New-Fill for facial atrophy

Lipodystrophy associated with lower CD4+ T cell counts

Peripheral neuropathy update

Leptin reverses lipodystrophy in diabetic patients

Meeting calls for NHS funding and training to provide repair treatment for people with facial lipoatrophy

Hepatic injury with nevirapine related to drug level and hepatitis C infection

It may be important to screen and treat riboflavin deficiency in patients on nucleoside analogues

Managing the metabolic side effects of antiretroviral therapy

Intensive diet and exercise regimen may help fight lipodystrophy

Avascular necrosis (AVN) may be increasingly common in HIV-positive patients

Rheumatological complications associated with the use of indinavir and other protease inhibitors

Doubt over use of antioxidant vitamins for the prevention of coronary disease

Endocrine disorders complicate ARV treatment

Enteric coated didanosine significantly reduces nausea, bloating, GI upset

Elevated blood pressure in subjects with lipodystrophy

Fat distribution is strongly tied to metabolic disturbances in HIV lipodystrophy

Eating more often can reduce cholesterol levels

Further reports of benefits of polylactic acid for facial lipoatrophy

Prevalence of adverse events associated with potent antiretroviral treatment: Swiss HIV cohort study

Preventable factors linked to indinavir-associated renal complications

Nerve growth factor improves HIV-associated sensory neuropathy

Lipodystrophy in HAART-treated patients may have multifactorial aetiology

Rapidly ascending neuromuscular weakness associated with nucleoside analogues

FDA requests changes in product information for all antiretrovirals

Dihydrotestosterone for HAART-associated breast enlargement in men

Osteopenia seen in testosterone-deficient women with AIDS wasting

Corticosteroids linked to HIV-associated osteonecrosis

Dietary factors, metabolic abnormalities and fat redistribution

High incidence of reduced bone density found in HIV positive people

Severe hepatic injury common after HAART initiation

Lipodystrophy and metabolic complications

Lipodystrophy and metabolic disturbances

Adverse events with antiretrovirals

Carnitine for high triglycerides

Does efavirenz cause breast enlargement?

Fat malabsorption common cause of diarrhoea in HIV-positive patients

Dietary supplements can help with nelfinavir-related diarrhoea

HCV coinfection may have role in changes in body composition in HIV patients

Sexual dysfunction associated with protease inhibitor containing HAART

Nevirapine use linked to icteric hepatitis in some HIV-positive patients

Tattoos flare up from HAART

Treatment of hyperlipidemia in HIV-positive patients

Self-reported symptoms after starting HAART help predict adherence

Risk of lipodystrophy in HIV-positive treated with PIs: a prospective cohort study

Drugs need not be stopped because of neutropenia in HIV-positive patients

Prevalence and correlates of anaemia in a large cohort of HIV-positive women

HIV-related fatigue relieved by psychostimulants

Studies underway on metabolic side effects of antiretrovirals

Lactic acidosis in pregnant women receiving d4T (stavudine) and ddI (didanosine): EMEA issue statement

Plasma cysteine deficiency and decreased reduction of nitrososulfa-methoxazole with HIV Infection

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