HTB

2008

Restarting treatment after an interruption reduces the risk of serious events but CD4 recovery falls short of baseline levels

Very low rate of MTCT in women on HAART in UK and Ireland who achieve viral suppression

Predictors of mother to child transmission among women initiating HAART in pregnancy in a South African cohort

Maternal and infant outcomes from the DREAM programme

Nevirapine-resistant HIV present in the latent reservoir following single-dose nevirapine for MTCT prevention

Tenofovir plus FTC reduce NNRTI resistance following single dose nevirapine

Response to treatment after single dose NVP exposure in women

Response to treatment after single dose NVP exposure in infants

Other studies looking at birth outcomes

Infant prophylaxis for postnatal transmission

Antiretroviral drug concentrations in breast milk and breastfeeding infants

Maternal breastfeeding prophylaxis

Risk factors for breastfeeding transmission

UK cohort reports sexual HCV reinfection in at least 5% HIV-positive gay men following sustained response to treatment

MELD score predictive of pre-transplant mortality in HCV coinfected patients

Does abacavir decrease SVR rates with HCV treatment?

No effect of interferon maintenance therapy on fibrosis progression in non-responders

Stem cell transplant from HLA-matched CCR5-delta 32 deleted donor suppresses viraemia in recipient for 8 months without HAART

Risk factors for AIDS-defining and non AIDS-defining cancers

New PMTCT guidelines for South Africa (Feb 2008)

FDA approve 600mg darunavir tablet

US study changes use of abacavir/3TC in naive patients with viral load >100,000 copies based on DSMB recommendation

A gutsy talk, and a new paper: report from third workshop on HIV persistence

Managing stigma – report into gay and bisexual African men with HIV released

Volume 9 Number 3/4 March/April 2008 PDF

Volume 9 Number 1/2 January/February 2008

CROI 2008 – 12 key areas of research: non-technical summary of 25 studies and presentations

Volume 9 Number 1/2 January/February 2008 PDF

15th Conference on Retroviruses and Opportunistic Infections, 2-6 February 2008, Boston

Increased risk of myocardial infarction associated with abacavir and ddI

Position statement by the D:A:D steering committee

3rd International Workshop on Targeting HIV Entry, 7-9 December 2007, Washington DC

CXCR4-using HIV found in 8.5% during early HIV infection

Background drugs and low maraviroc levels explain resistance in Motivate studies

38th World Conference on Lung Health of the Union Against TB and Lung Disease, December 2007, Cape Town

Treatment outcomes in patients who received rifampicin with nevirapine or efavirenz

Boehringer fails to register tipranavir in Brazil after using Brazilian patients in registrational study

Raltegravir approved in Europe and available in the UK

Paediatric lopinavir/r receives positive opinion from EMEA

Etravirine (TMC-125) approved in the US

Changes to atazanavir product label in US

US treatment guidelines updated (2008)

HIV-positive adults with CD4 >500 cells/mm3 have similar mortality rates as the general population after seven years ARV treatment

Dual-class mutations affection RTI and NNRTI may be common in experienced patients

Atazanavir exposure in pregnancy

Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-positive pregnant women

Predictors of mortality in untreated HIV-positive children

Pharmacokinetics of lopinavir/ritonavir in infants less than 12 months of age

Comparative study of pegylated interferon formulations in HCV monotherapy

Probing HIV dependence on host proteins

An eye on the benign: pathogenesis lessons from non-pathogenic SIV infections

HIV awakens retroviral zombies from cellular slumber

Immune activation correlates with CD4 T cell declines in HIV controllers

Darunavir/ritonavir interaction with clarithromycin warrants caution

Updated and new resources on HIV drug interactions

58th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)

Targeting HIV Entry: 3rd International Workshop

PLoS Medicine

Breakthroughs in immunology

Multiple roles of CCR5 in infectious diseases

New resources from HIV inSite

New advocacy site: HIV and pregnancy

CROI 2008: 12 key areas of research – non-technical summary of 25 studies and presentations

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