BHIVA update guidance on shingles vaccine
9 January 2024. Related: Guidelines, Coinfections and complications, Basic science and immunology, Vaccines and microbicides, BHIVA news.
Basic science and immunology
CD4:CD8 ratio recovery reduces with higher age when starting ART
1 December 2023. Related: Treatment strategies, Basic science and immunology.
Defective HIV proviral particles linked to persistent inflammation and immune activation despite effective ART
1 September 2023. Related: Pathogenesis, Basic science and immunology.
IAS 2023: Rapporteur summary Track A – basic science
1 September 2023. Related: Conference reports, Cure-related research, Basic science and immunology, Vaccines and microbicides.
Cannabis does not reduce T cells in people living with HIV
1 September 2023. Related: Pathogenesis, Basic science and immunology.
Review of idiopathic lymphocytopenia
1 June 2023. Related: Coinfections and complications, Basic science and immunology.
CROI 2022: Telomere shortening associated with TAF but not TDF in CHARTER study
1 March 2022. Related: Conference reports, Basic science and immunology, Ageing and life expectancy.
HIV-associated reductions in telomere length are stopped by effective ART
7 February 2022. Related: Coinfections and complications, Basic science and immunology, Ageing and life expectancy.
A step forward for AAV-mediated delivery of bNAbs
17 April 2020. Related: Conference reports, Cure-related research, Basic science and immunology.
Science journal retracts article linking CCR5 deletion to reduced life expectancy
18 October 2019. Related: Basic science and immunology.
Gene editing to eliminate HIV from mice: misleading and wrongly reported in media coverage
17 July 2019. Related: Cure-related research, Basic science and immunology.
New online animation of HIV lifecycle
21 May 2018. Related: Basic science and immunology, On the web.
Elite controllers: sex differences and factors associated with loss of immune control
30 March 2018. Related: Cure-related research, Basic science and immunology.
Effects of the anti-inflammatory antibody canakinumab on heart disease and cancer: implications for HIV?
28 November 2017. Related: Side effects, Coinfections and complications, Basic science and immunology.
HIV remission news from IAS 2017
10 August 2017. Related: Conference reports, Cure-related research, Basic science and immunology.
Natural history of elite controllers
26 June 2017. Related: Basic science and immunology.
HIV superinfection is associated with specific HLA types
26 June 2017. Related: HIV prevention and transmission, Basic science and immunology.
Immune-based therapy canakinumab reduces inflammatory markers in HIV positive people on ART
24 April 2017. Related: Conference reports, Treatment strategies, Basic science and immunology.
HIV cure research and basic science: capsules from CROI 2017
24 April 2017. Related: Conference reports, Cure-related research, Basic science and immunology.
Flagging the HIV reservoir: a potential new marker for CD4 cells hiding HIV
24 April 2017. Related: Cure-related research, Basic science and immunology.
Soluble CD163 as a marker of CMV mediated immune activation
27 February 2017. Related: Basic science and immunology.
Levels of CMV antibody are linked to HIV progression and immune activation in Ugandan women
27 February 2017. Related: Basic science and immunology.
New HBV drugs and non-viral liver disease in HIV positive people
1 June 2016. Related: Conference reports, Hepatitis coinfection, Basic science and immunology.
Developing multi-pronged antibodies to target the HIV reservoir
1 February 2016. Related: Cure-related research, Basic science and immunology.
Combining PKC agonists and bromodomain inhibitors to reverse HIV latency
1 October 2015. Related: Cure-related research, Basic science and immunology.
Estimating how frequently latent HIV reactivates
1 October 2015. Related: Cure-related research, Basic science and immunology.
Innate immunity and HIV DNA declines in panobinostat recipients
1 August 2015. Related: Cure-related research, Basic science and immunology.
Other short reports from BHIVA:
1 June 2015. Related: Conference reports, Antiretrovirals, Paediatric care, Basic science and immunology.
Timing of very early ART to limit early HIV-related mucosal dysfunction
1 June 2015. Related: Basic science and immunology.
Broad CD8 T cell responses are required to overcome dominance of CTL escape in the latent HIV reservoir
1 June 2015. Related: Basic science and immunology.
Broadly neutralising antibody suppresses HIV in clinical trial
1 June 2015. Related: Basic science and immunology.
Is HIV weakening over time? Unlikely, and a sense of déjà vu…
29 January 2015. Related: Basic science and immunology.
Quantification of latent HIV induction by vorinostat
29 January 2015. Related: Basic science and immunology.
Three papers on macrophages and HIV infection
1 December 2014. Related: Cure-related research, Basic science and immunology.
Stemming the flow from HIV reservoirs with neutralising antibodies
1 October 2014. Related: Cure-related research, Basic science and immunology.
Effects of long-term ART initiated during primary HIV infection on reservoir size
1 August 2014. Related: Cure-related research, Basic science and immunology.
Molecular events in HIV neutralising antibody development
1 August 2014. Related: Basic science and immunology, Vaccines and microbicides.
Incidence of HIV dual infections in US men who have sex with men
27 May 2014. Related: Basic science and immunology.
Reassessing the role of HDAC inhibitors in cure research
27 May 2014. Related: Cure-related research, Basic science and immunology.
More on the links between the CD4/CD8 ratio, immunological perturbations, and risk of illness and death
27 May 2014. Related: Cure-related research, Basic science and immunology.
Reports of a second baby possibly cured of HIV: uncertainty remains
24 March 2014. Related: Conference reports, Cure-related research, Basic science and immunology.
Updates on SB728-T, a CCR5-targeting gene therapy
24 March 2014. Related: Conference reports, Cure-related research, Basic science and immunology.
The prognostic value of interleukin-6 and D-dimer levels in primary HIV infection
24 March 2014. Related: Basic science and immunology.
HIV reservoir: CD4 T stem cells may facilitate long-term persistence
24 March 2014. Related: Basic science and immunology.
Update published on the first Berlin patient
24 March 2014. Related: Basic science and immunology.
Poor CD4 T cell recovery despite HIV suppression linked to increased morbidity and mortality
24 March 2014. Related: Basic science and immunology.
The relevance of the CD4/CD8 ratio in the ART era
24 March 2014. Related: Basic science and immunology.
First human trial of AAV as a delivery vehicle for HIV neutralising antibodies gets underway
24 March 2014. Related: Basic science and immunology.
HIV rebounds in Boston stem cell transplant recipients
1 February 2014. Related: Cure-related research, Basic science and immunology.
Dual HIV infection in long term nonprogressor elite controllers
1 December 2013. Related: Basic science and immunology.
Circulating memory T follicular helper cells correlate with the development of broadly neutralising antibody responses against HIV
1 October 2013. Related: Cure-related research, Basic science and immunology.
No viral load rebound off-ART following stem cell transplant: two “cure” cases using reduced intensity conditioning chemotherapy and CCR5 d-32 negative donors
25 July 2013. Related: Conference reports, Cure-related research, Basic science and immunology.
HIV cure research: further capsules at IAS 2013
25 July 2013. Related: Conference reports, Cure-related research, Basic science and immunology.
Sad news regarding attempt to duplicate the cure achieved in Timothy Brown
25 July 2013. Related: Basic science and immunology.
ART reduces HIV reservoirs in elite controllers: implications for cure research
25 July 2013. Related: Basic science and immunology.
Basic research highlights from CROI 2013
29 May 2013. Related: Conference reports, Basic science and immunology.
Probiotic/prebiotic supplement combination shows benefits in SIV-infected pigtailed macaques
29 May 2013. Related: Conference reports, Basic science and immunology.
Searching for HIV in Timothy Brown, the Berlin Patient
29 May 2013. Related: Cure-related research, Basic science and immunology.
Reviewing strategies for draining HIV reservoirs
29 May 2013. Related: Cure-related research, Basic science and immunology.
Can a route to broadly neutralising antibodies be traced?
29 May 2013. Related: Basic science and immunology.
CD4 T cells specific for different pathogens vary in susceptibility to HIV infection
1 April 2013. Related: Basic science and immunology.
Attack of the killer helpers (part two)
1 February 2013. Related: Basic science and immunology.
Lymph node fibrosis, CD4 T cells and immune reconstitution
1 February 2013. Related: Basic science and immunology.
New research on gut CD4 T-cell depletion and HIV pathogenesis
1 February 2013. Related: Basic science and immunology.
Hopes raised by HDAC inhibitor, but uncertainties remain
1 December 2012. Related: Cure-related research, Basic science and immunology.