August 2022

Contents

Editorial

• HTB August 2022 (3 August 2022)

• Sending unused meds to Ukraine: emergency appeal

• Organisations to support Ukraine

Special reports

• MPX vaccine update – access, doses, safer MPX sex

• Taking a break from monkeypox: four weeks out for August

Conference reports

• 24th International AIDS Conference (AIDS 2022): first reports

• Dolutegravir-based ART in children and adolescents: effective in six African countries

• Early data on injecting CAB/RPV-LA into thigh muscle

• Simplifed lenacapavir dosing: PK results in HIV negative study

• Doxycycline PEP significantly reduces STIs in people at high risk of infections

• Another possible HIV cure case after stem cell transplantation for cancer; example of extended post-treatment control in Spain

• Other cure-related sessions at AIDS 2022

• Selected reports launched at AIDS 2022

Guidelines

• US guidelines on HIV-related OIs online for comment

mpox (monkeypox)

• BHIVA include efficacy data on HIV and monkeypox vaccine: updated statement

• WHO declares the monkeypox pandemic a global health emergency

• UK organisations call for £51 million to urgently tackle monkeypox crisis

• EMA approves Imvanex vaccine against monkeypox in EU

• International study of 528 monkeypox (MPX) cases: results from the 2022 outbreak need to inform new management guidelines

• Tecovirimat to treatment monkeypox: an urgent need for both RCT and expanded access

• Monkeypox DNA detected at high levels in saliva and is common in semen and other samples

• Risk of monkeypox being infectious on hard surfaces and soft materials: guidelines for effective cleaning

• Outcomes of 54 cases of monkeypox (MPX) in London: fewer early symptoms but higher rates of genital lesions – urgency of funding sexual health

• Ending the monkeypox outbreak through vaccination, contact tracing and early diagnosis

• US doctors think it is already too late to contain monkeypox

Coinfections and complications

• Case report of COVID-19 transmission from sneezing cat

• Accumulating SARS-CoV-2 mutations in prolonged COVID-19 in advanced HIV off-ART

• No benefit from TDF/FTC against COVID-19

PDFs

• HTB: no. 8 (3 August 2022) PDF downloads