HTB

Conference reports

Case of multi-drug resistant (MDR) rapid progressor

Case report of antibody reversion and negative viral load four-years after treatment discontinuation

24-week efficacy of TMC114 in PI-experienced patients

Maturation inhibitor shows anti-HIV activity in single dose pilot study

New antiretrovirals at 12th CROI

Absolute risk is modest, but cumulative cardiovascular risk of HAART over five years is similar to ‘ever smoked’: new data on gender and age

Omega-3 supplement effective to reduce triglycerides

Entecavir is effective against 3TC-resistant hepatitis B

Switch to tenofovir from AZT or d4T improves fat loss and improves lipid parameters compared to abacavir

Continued use of a thymidine analogue may limit benefit from rosiglitazone when used to treat lipoatrophy

Tenofovir is non-inferior to adefovir for the treatment of hepatitis B in HBV-HIV co-infected patients

7th International Congress on Drug Therapy in HIV Infection (ICDTHI), 14-18 November 2004, Glasgow

Nandrolone decanoate combats HIV-related weight loss: results from three randomised studies

Atazanavir boosts intracellular saquinavir levels: data on important new dual-boosted regimen

Marked variability in plasma atazanavir levels: importance of ritonavir boosting and TDM

Effective switching to atazanavir/ritonavir in clinical practice

Ritonavir boosting may not overcome interaction between atazanavir and nevirapine

Nevirapine associated adverse events in a cohort of pregnant women

Higher nevirapine doses for children leads to better outcome

TDM in Ugandan study highlights importance of refridgerated ritonavir

Responses to TB treatment in HIV positive and HIV negative patients in the UK

800mg efavirenz may not be needed with rifampicin-based TB regimens, especially in African patients

EuroSIDA shows HIV-HCV coinfected patients more likely to stop HAART because of side effects

Lower d4T dose maintains virologic suppression and CD4 increases

6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV (IWADRLH) 26-28 October 2004, Washington

Nucleoside analogue-related mitochondrial toxicity and link to lipoatrophy: effect of non-thymidine analogues abacavir and tenofovir

Nucleosides reduce PPAR-gamma: a role for rosiglitazone without thymidine analogues?

Potential for uridine to treat mitochondrial toxicity: still only in vitro data

25% patients take Kaletra on an empty stomach: dietary advice often missed at ‘centre of excellence’

rHGH reduces central fat accumulation in adolescent lipodystrophy

Weight loss is associated with elevated PBMC proviral DNA levels

Coronary artery bypass graft is safe in HIV-positive patients but shows higher risk of longer term events

Endothelial dysfunction similar in ARV-experienced and -naive patients

Pravastatin improves lipid profiles but not endothelial function

Indinavir impairs endothelial function without insulin resistance

Treatment interruptions improve lipids within four weeks: IL-2 has no metabolic effect

Improvement of lipids following switch to tenofovir

HCV coinfection linked to discontinuing ART due to toxicity

Restorative treatments for HIV-associated lipoatrophy

44th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 30 October-2 November 2004, Washington

Tipranavir in treatment experienced patients: results from RESIST-1

Reverset: first data in patients with nucleoside resistance

Poor response with tenofovir and ddI backbone causes early study termination

Paradoxical CD4 response with tenofovir and ddI backbone

Tenofovir/FTC backbone outperforms AZT/3TC (Combivir) with efavirenz in treatment naive patients; reduced toxicity drives ITT viral efficacy

Limited stability of lopinavir/r (Kaletra) above 25°C

Atorvastatin requires dose reduction with tipranavir/r

Once-daily T-20 is less effective than twice daily: lower potency is related to C trough

Further genetic link to efavirenz absorption

Long-term response to FTC in children is similar to adults

Side effects update: hypersensitivity, heart, bones

XV International World AIDS Conference, 11-16 July 2004, Bangkok

Women and HIV: research directions

The X4 files: sampling the science on HIV co-receptors in Bangkok

10th BHIVA Autumn Conference 8-9 October 2004, London

BHIVA audit on management of HIV/Hepatitis coinfection

XV International World AIDS Conference, 11-16 July 2004, Bangkok

Dollars, commerce, politics and prejudice all present obstacles to scaling up access to treatment in resource poor countries

MTCT programmes in South Africa: nevirapine and the minister

Urgency of global access to ARV treatment for IV drug users

Replace myths with evidence–based policies on IV drug use

Adding Combivir to single dose nevirapine for reduction of MTCT significantly reduces resistance

Lopinavir/r levels reduced during pregnancy

Another chance for 3TC in patients with M184V mutation?

Kaletra monotherapy: small studies and early data

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