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UK guide to PrEP (2025)

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Background

  • 2025 update and getting PrEP in the UK
  • What is PrEP?
  • Who can take PrEP?
  • Who should NOT take PrEP?
  • How well does PrEP work?
  • PrEP and side effects
  • PrEP and drug resistance
  • PrEP and other STIs
  • Does PrEP interact with food or other medications?

PrEP for women

PrEP for trans and non binary people

PrEP and sex work

Buying PrEP in the UK including online

Before you start PrEP

Routine care if you have already started PrEP

  • Other considerations

How to start and stop PrEP

  • Daily PrEP dosing
  • Event-based dosing
  • Examples of event-based 2:1:1 and 2:7 dosing

Other tips on how to take PrEP

  • What to do if you miss a pill
  • Tips on taking PrEP
  • Is PEP recommended if I am on PrEP?
  • Can I switch between daily and event-based dosing?
  • Can I stop PrEP completely?

Updates in this edition, credits and disclaimer

Links and further information

PDF

References

Feedback

About our guides

Information about how we produced this guide and the importance of using language that is direct and easy to understand.

This includes information on how to write non technical medical information that may be useful as a resource for other organisations.

Last updated: 1 February 2025.

UK guide to PrEP (2025)

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