No difference in outcomes for children initiating treatment with a protease inhibitor or an NNRTI nor with viral load switching strategies in PENPACT-1
26 August 2010. Related: Conference reports, Antiretrovirals, Paediatric care.
Conference reports
Tablets more acceptable than syrups in the ARROW trial
26 August 2010. Related: Conference reports, Antiretrovirals, Treatment strategies, Paediatric care.
Paediatric formulation of TMC 278
26 August 2010. Related: Conference reports, Antiretrovirals, Paediatric care.
Smoking and atazanavir levels
26 August 2010. Related: Conference reports, PK and drug interactions.
Darunavir/ritonavir and rosuvastatin
26 August 2010. Related: Conference reports, PK and drug interactions.
Lime juice is not a microbicide: do not try at home
26 August 2010. Related: Conference reports, Women's health, HIV prevention and transmission.
2nd Joint Conference of BHIVA with BASHH, 20-23 April 2010, Manchester
1 June 2010. Related: Conference reports.
HAART use among women in UK receiving treatment prior to conception
1 June 2010. Related: Conference reports, Pregnancy.
Duration of ruptured membranes and vertical transmission in the UK
1 June 2010. Related: Conference reports, Pregnancy.
Significant rates of unplanned pregnancies among young women born with HIV
1 June 2010. Related: Conference reports, Pregnancy, Paediatric care.
Route of HCV transmission in HIV-positive gay men is unlikely to be from semen
1 June 2010. Related: Conference reports, Hepatitis coinfection.
75% HIV-positive children have insufficient levels of Vitamin D
1 June 2010. Related: Conference reports, Paediatric care, Side effects, Weight, diabetes, metabolic complications.
Increase in LGV cases in gay men reported in the UK
1 June 2010. Related: Conference reports.
High rates of osteopenia and osteoporosis: importance of DEXA monitoring
1 June 2010. Related: Conference reports, Side effects, Weight, diabetes, metabolic complications.
Summaries of other studies
1 June 2010. Related: Conference reports, HIV prevention and transmission.
11th International Workshop on Clinical Pharmacology of HIV Therapy, 7-9 April, 2010, Sorrento, Italy
1 June 2010. Related: Conference reports, PK and drug interactions.
Atazanavir absorption maximised with food
1 June 2010. Related: Conference reports, PK and drug interactions.
Methadone levels reduced moderately by rilpivirine
1 June 2010. Related: Conference reports, PK and drug interactions.
Maraviroc 150mg once-daily achieves target concentrations with atazanavir/ritonavir
1 June 2010. Related: Conference reports, PK and drug interactions.
Raltegravir and unboosted atazanavir
1 June 2010. Related: Conference reports, PK and drug interactions.
Raltegravir dose adjustment not required for patients on dialysis
1 June 2010. Related: Conference reports, PK and drug interactions.
Raltegravir and darunavir pharmacokinetics in liver disease
1 June 2010. Related: Conference reports, PK and drug interactions.
Tenofovir may require closer renal monitoring in older patients
1 June 2010. Related: Conference reports, PK and drug interactions, Injecting drug users.
Effect of age on atazanavir, darunavir, raltegravir and etravirine
1 June 2010. Related: Conference reports, PK and drug interactions.
Proposed approach to measuring TDM for raltegravir
1 June 2010. Related: Conference reports, PK and drug interactions.
Increased bilirubin levels when atazanavir is dosed twice-daily
1 June 2010. Related: Conference reports, PK and drug interactions.
17th Conference on Retroviruses and Opportunistic Infections (CROI) 16-19 February 2010, San Francisco
1 June 2010. Related: Conference reports.
HIV reinfection cases reported at CROI
1 June 2010. Related: Conference reports, HIV prevention and transmission, Virology.
Hepatitis studies: IL28B genetics, HCV survival, FibroScan in acute HCV, MSM reinfection and responses to transplantation
1 June 2010. Related: Conference reports, Hepatitis coinfection.
Poor bioequivalence with crushed and dissolved tablets
1 June 2010. Related: Conference reports, Paediatric care, PK and drug interactions.
Initial PK, safety and 12 week efficacy of raltegravir chewable tablets in children 6-11 years
1 June 2010. Related: Conference reports, Paediatric care.
PK of efavirenz in children dosed according to WHO weight bands
1 June 2010. Related: Conference reports, Paediatric care.
Virological and immunological responses in infants enrolled in the CHER trial
1 June 2010. Related: Conference reports, Paediatric care.
Darunavir-associated mutations in PI-naive and PI-experienced children in the UK
1 June 2010. Related: Conference reports, Paediatric care, Drug resistance.
HIV persistence, raltegravir/maraviroc intensification and immunology
1 June 2010. Related: Conference reports, Basic science and immunology.
17th Conference on Retroviruses and Opportunistic Infections (CROI), 16-19 February 2010, San Francisco
2 April 2010. Related: Conference reports.
Treatment reduces infections by over 90%: a theme that is here to stay
2 April 2010. Related: Conference reports, Antiretrovirals, HIV prevention and transmission.
ACTG 5205: atazanavir/ritonavir vs efavirenz in treatment naive patients
2 April 2010. Related: Conference reports, Antiretrovirals, Side effects, Weight, diabetes, metabolic complications.
Pipeline compounds and new approaches to treatment
2 April 2010. Related: Conference reports, Antiretrovirals.
Clinical benefits of stopping smoking: CVD and CHD risk returns to that of previous smoker in HIV-positive people within three years
2 April 2010. Related: Conference reports, Weight, diabetes, metabolic complications, Cancer and HIV.
HIV increases the risk of lung cancer, independent of smoking status
2 April 2010. Related: Conference reports, Cancer and HIV.
HIV positive people in the HOPS cohort have 4-fold risk of fracture compared to general population in the US
2 April 2010. Related: Conference reports, Side effects.
Vitamin D deficiencies in HIV management
2 April 2010. Related: Conference reports, Side effects, Weight, diabetes, metabolic complications.
OCTANE 2: nevirapine and lopinavir/r are similar when used with tenofovir and FTC in treatment-naive women
2 April 2010. Related: Conference reports, Pregnancy.
HIV incidence and retesting in pregnancy
2 April 2010. Related: Conference reports, Pregnancy.
Efavirenz use in pregnancy and birth outcomes
2 April 2010. Related: Conference reports, Pregnancy.
Pregnancy outcomes in women using non-AZT HAART in Europe
2 April 2010. Related: Conference reports, Pregnancy.
When should HAART be initiated in pregnancy to achieve an undetectable viral load?
2 April 2010. Related: Conference reports, Pregnancy.
Pregnancy outcomes in infants exposed to maternal antiretrovirals in utero
2 April 2010. Related: Conference reports, Pregnancy, Paediatric care.
Maternal TB, HIV and pregnancy
2 April 2010. Related: Conference reports, Women's health, Pregnancy, TB coinfection.
12th European AIDS Society Conference (EACS), 11-14 November 2009, Cologne
21 February 2010. Related: Conference reports.
Screening for anal cancer recommended for HIV positive men
21 February 2010. Related: Conference reports, Cancer and HIV.
Once-daily darunavir/r monotherapy is suboptimal as initial regimen in treatment-naive people
21 February 2010. Related: Conference reports, Antiretrovirals.
Central fat accumulation remains a significant problem in patients starting HAART after 2005 with higher incidence in women compared to men
21 February 2010. Related: Conference reports, Women's health, Side effects, Weight, diabetes, metabolic complications.
Alendronate improves bone mineral density in HIV positive people with osteoporosis at 96 weeks
21 February 2010. Related: Conference reports, Side effects.
TMC278 did not show teratogenic potential in animal models
21 February 2010. Related: Conference reports, Pregnancy.
Etravirine pregnancy data from five cases: no dose adjustment required
21 February 2010. Related: Conference reports, Pregnancy.
No clinically relevant interactions between TMC278 and oral contraceptives (norethindrone plus ethinylestradiol)
21 February 2010. Related: Conference reports, Women's health, PK and drug interactions.
Gender-based differences in patients receiving antiretroviral therapy
21 February 2010. Related: Conference reports, Women's health.
Pilot PK study of two generic paediatric formulations of lopinavir/ritonavir vs originator products
21 February 2010. Related: Conference reports, Paediatric care, PK and drug interactions.
Other selected PK and drug interaction summaries from EACS
21 February 2010. Related: Conference reports, PK and drug interactions.
11th International Workshop on Adverse Drug Reactions and Co-morbidities in HIV (IWADR) 26-28 October 2009, Philadelphia
20 February 2010. Related: Conference reports, Side effects.
The HCV pipeline efficacy and side effect of compounds in Phase 3 studies
20 February 2010. Related: Conference reports, Hepatitis coinfection.
12th European AIDS Society Conference (EACS) 11-14 November 2009, Cologne
31 December 2009. Related: Conference reports.
EACS releases three updated management guidelines (December 2009)
31 December 2009. Related: Conference reports, Guidelines.