HTB

Conference reports

The HCV pipeline – efficacy and side effect of compounds in Phase 3 studies

12th European AIDS Society Conference (EACS) 11-14 November 2009, Cologne

EACS releases three updated management guidelines (December 2009)

11th International Workshop on Adverse Drug Reactions and Comorbidities in HIV (IWADR) 26-28 October 2009, Philadelphia

Intermuscular tissue is decreased in HIV infection

High incidence and risk factors for diabetes in French cohort

Gender and race differences in lipodystrophy symptoms

Lipodystrophy is common in children from three European cohorts

Visceral adipose tissue returns to baseline after stopping therapeutic intervention with rHGH

Reduced levels of vitamin D in patients taking efavirenz

Association between inflammation and sleep apnea in the MACS cohort

Sports supplements impact on serum creatinine and eGFR markers of renal function

9th AIDS Vaccine Conference 19-22 October 2009, Paris

Thai HIV Vaccine Trial results presented and published

49th International Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 12-15 September 2009, San Francisco

Smoking masks the long-term benefits of HAART on lung function

Recent ARVs and the blood/brain barrier: CSF drug concentrations of darunavir/r and raltegravir

Raltegravir body composition study: 48-week DEXA results

Alcohol and marijuana may reduce drug levels of atazanavir and efavirenz

Other drug interaction studies at ICAAC

5th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 19-23 July 2009, Cape Town

Early infant diagnosis

Difficulties with implementation

Infant outcomes

Improved neurodevelopmental outcomes

Treating children exposed to single dose nevirapine for PMTCT

Using a nevirapine-containing fixed dose combination in the CHAPAS trial

Once a day lamivudine and abacavir, and abacavir hypersensitivity in the ARROW trial

5th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 19-23 July 2009, Cape Town

First results of new integrase compound: GSK1349572

Raltegravir in treatment-naive patients

Nevirapine vs atazanavir/ritonavir in treatment-naive patients: ARTEN study

Darunavir/r monotherapy studies

Maraviroc results similar to efavirenz when analysed using more sensitive tropism test

Lipid and metabolic changes with ARV combinations

Maximal suppression achieved with three drugs: no additional virological impact of raltegravir intensification

Tenofovir and renal safety

Time from seroconversion to treatment in Europe and Africa

Pharmacokinetics of atazanavir/ritonavir during pregnancy

Presentation with late stage HIV in women diagnosed during pregnancy

Low transmission rates and favourable pregnancy outcomes reported in the DREAM study

Pregnancy rates and outcomes among women in the DART trial

Pregnancy outcomes in HAART exposed infants in Johannesburg

Efavirenz conceptions in Soweto

Impact of regimen and duration of therapy on risk of mother-to-child HIV transmission in Johannesburg

A cost-effectiveness analysis of the OCTANE trial

The PEARL study

Results from HSV-2 acyclovir studies

Overview of TB-related studies at IAS

5th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 19-23 July 2009, Cape Town

Five-year survival rates of 87% without routine CD4 or laboratory monitoring in DART study demonstrate an important model for ARV access programmes

Biomarkers associated with mortality: long-term follow up from SMART

Update on Interleukin-2 clinical trials

Influenza vaccine effective in HIV-positive adults

Reducing HIV transmission during breastfeeding

Treating children previously exposed to single dose nevirapine

10th International Workshop on Clinical Pharmacology of HIV Therapy, 15-17 April 2009, Amsterdam

Monotherapy study may explain previous poor clinical results when abacavir and tenofovir are used in combination

Interactions between ARVs and antimalarials atovaquone and proguanil

Four weeks lopinavir/r to cover functional monotherapy when stopping HAART

Efavirenz-related studies: genetics, smoking and TDM

Atazanavir: a suitable case for TDM?

Raltegravir PK in blood plasma and the genital tract

A CYP2B6 haplotype influences nevirapine plasma concentrations following a single dose to reduce mother to child transmission

Population pharmacokinetic model of nevirapine maternal to infant transfer through breastfeeding

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