Conference reports

Bone loss in SMART study

Parathyroid hormone and vitamin D levels in patients using tenofovir

Haemoglobin A1c (HbA1c) may underestimate glycaemia in patients with diabetes on HIV therapy

Statin use in HIV-positive patients

HIV reinfection reported in 10% of couples in Zambian study

Drug interaction studies with approved drugs

Non alcoholic fatty liver disease (NAFLD) is common among HIV-positive patients

17th International AIDS Conference, 3-8 August 2008, Mexico City

Abacavir and heart disease: SMART study supports an abacavir-associated increased risk of cardiovascular disease

HAART use in pregnancy and preterm delivery and low birth weight

Reasons for mother to child transmission in England

New paediatric formulations of ARVs

3rd International Transmission Workshop, 1-2 August 2008, Mexico City

Intermittent tenofovir/FTC PrEP offers monkeys some protection

Tenofovir/FTC gel protects female monkeys from SHIV

Recently infected HIV-positive Quebec residents cause more than half of new cases

Common estimate of heterosexual HIV transmission risk sometimes far too low

10 key areas of research: non-technical summary of studies and presentations from Mexico

XVII International HIV Resistance Workshop (IHDRW), 6-10 June 2008, Sitges

Integrase inhibitor resistance and cross-resistance: weighing viral fitness and the option to benefit from second-generation compounds

Understanding etravirine susceptibility: new weighted genotype score and phenotypic cut-offs

Pipeline antiretrovirals: IDX899, CHX157 and bevirimat

Lack of virological impact of treatment intensification in suppressed patients supports latent viral reservoir as source of residual viraemia

NNRTI resistance in infants prophylaxed with single-dose nevirapine varies by the timing of infection

Detecting viral tropism: impact of a more sensitive Trofile (ES) assay

Low frequency K103N mutations are associated with poor virological response to NNRTI based therapy

14th Annual BHIVA Conference, 23-25 April 2008, Belfast

Bone problems raised in several UK studies

Late diagnosis in adolescence of vertically acquired HIV infection

Case study of multi-drug resistant woman receiving newer antiretroviral drugs in pregnancy

Predictors of treatment failure in Western Cape, South Africa

Late pregnancy loss in HIV-positive women

Renal tubular dysfunction with tenofovir-based HAART in four vertically infected adolescents

15th Conference on Retroviruses and Opportunistic Infections, Boston, 2-6 February 2008

The unmet need for contraception services for women receiving ART

Valacyclovir decreases plasma and genital viral loads in HSV-2/HIV-1 co-infected women

HPV genotypes in HIV-positive women in Zimbabwe and Uganda

14th Annual BHIVA Conference, 23-25 April 2008, Belfast

Overview of MRC studies in 2008

Initial results of BHIVA audit of HIV-related inpatient and day care in the UK

Monitoring patients on antiretroviral therapy in resource-limited settings with viral load, CD4 count, or clinical observation alone

Lower bilirubin increases in HCV-positive patients using atazanavir

Cases of ventricular tachycardia and atazanavir/r and methadone

Choice of ARVs for people after organ transplantation

Use of fibroscan as non-invasive alternative to liver biopsy in HCV/HIV coinfection

New-fill used to treat lipoatropy in feet

Effect of 100mg ritonavir once- and twice-daily on lipids and cardiovascular markers in HIV-negative volunteers

15th Conference on Retroviruses and Opportunistic Infections, Boston, 2-6 February 2008

Immediate HAART reduces death and AIDS progression over 48 weeks in patients with acute OIs

Utility of routine viral load, CD4 count and clinical monitoring among HIV-positive adults in rural Uganda

Implementation of more complex regimens for prevention of mother-to-child transmission of HIV in Rwanda

The estimated cost of switching from d4T to TDF in South Africa

Gender differences in viral load by CD4 count in men and women

Immune reconstitution inflammatory syndrome in young children initiating ART

Complications with BCG vaccination in HIV-positive and negative infants: CHER Study

The association between clinical characteristics and HIV-infection in very young infants

Safety and efficacy of boosted darunavir in treatment-experienced children and adolescents at 24 weeks

Responses to atazanavir-containing HAART in treatment-naive children in South Africa

Initial growth, CD4, and viral load responses to HAART in Ugandan compared to UK/Irish HIV-positive children

Paediatric pharmacokinetic studies

A pilot study of three treatment strategies for HIV-positive infants

15th Conference on Retroviruses and Opportunistic Infections, 2-6 February 2008, Boston

Atazanavir/r vs lopinavir/r in treatment-naive patients: 48 week results

Baseline inflammation and coagulation markers and changes over four weeks during a treatment interruption are strongly linked to HIV viraemia and risk of mortality

Restarting treatment after an interruption reduces the risk of serious events but CD4 recovery falls short of baseline levels

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