HTB

2000

Mitochondrial toxicities of nucleoside reverse transcriptase inhibitors

HIV drug resistance testing: update

Exercise testing in HIV patients with random increased lactic acid levels: evidence for a reduced anaerobic threshold with a pattern of mitochondrial dysfunction

Letter: Project Inform nelfinavir potency concerns article

Accelerated bone mineral loss in HIV-positive patients receiving potent antiretroviral therapy

Antiretroviral therapy improves thymic output in some HIV-infected children

Didanosine systemic exposure in children similar with or without food, high interpatient variability suggests TDM to titrate individual dosages

CD8+-cell antiviral factors not restricted to cytotoxic T cells induced during HIV

What is Armenicum?

HIV-related anal cancer incidence increased in long-term survivors

Irreversible renal dysfunction linked to long-term indinavir therapy

Drug companies fail to conduct necessary post-marketing studies

Low level HIV replication despite good virological response may explain CD4+ cell decline in a patient receiving combination nucleoside analogue therapy

Phase III study of GM-CSF in advanced HIV disease

Women and HIV: is it really a biological difference?

Safety warning on amprenavir oral liquid

Volume 1 Number 3 June 2000 PDF

Third International Workshop on Salvage Therapy for HIV Infection, April 12-14, 2000, Chicago, USA

Clinical studies of indinavir/ritonavir as salvage therapy

Indinavir plus ritonavir: might exposure to higher levels of indinavir overcome protease resistant HIV and prove useful to ‘rescue’ previously failed protease inhibitor based combinations?

First International Workshop in Clinical Pharmacology in HIV Therapy, 30-31 March 2000, Noordwijk, Netherlands

TDM: standardisation and quality control

TDM in clinical practice

ATHENA – Early results from first randomised study of clinical benefits of TDM

TDM for individualising dosing – practicality and efficacy for PIs and RTIs

TDM and adherence

Drug interactions: amprenavir, saquinavir, ABT-378/r (lopinavir/r), indinavir, efavirenz, ritonavir

L-Acetyl Carnitine (LAC) improves symptoms of peripheral neuropathy (PN): evidence for increases in cutaneous innervation

ABT-378/r (lopinavir) now available on named patient basis in UK

Enteric coated ddI available on named patient basis in UK

Nelfinavir potency concerns

Liquid formulation of efavirenz available for children in the uk on named patient basis

Most reconstituted CD4 cells naive after HAART in children with HIV

GM-CSF beneficial for patients with advanced HIV disease

Decreased bone mineral density and HIV protease inhibitors

A view from the lab: interview with Professor Clive Loveday

EMEA public statement on Viramune (nevirapine): severe and life-threatening cutaneous and hepatic reactions

Volume 1 Number 2 May 2000 PDF

Welcome to HIV Treatment Bulletin (incorporating DrFax)

7th Conference on Retroviruses and Opportunistic Infections (ROI), January 30-February 2 2000, San Francisco

Paediatrics: children are not small (or miniature) adults

HIV-positive women, pregnancy and newborns

Flu-like symptoms of severe acute HIV infection develop after suspension of HAART

Non-clade B virus: epidemiology, testing strategies and resistance

Public Health Service (US) releases updated guidelines for treatment of HIV positive pregnant women

French National Drug Agency re-commends use of IL-2 if HAART does not lead to an increase in CD4 count to greater than 200 cells/mm3

St John’s Wort: message from Professor A Breckenridge, Chair, Committee on Safety of Medicines.

Interactions of St John’s Wort (Hypericum perforatum) preparations

Important safety information for people taking St John’s Wort preparations

French National Drug Agency re-commends use of IL-2 if HAART does not lead to an increase in CD4 count to greater than 200 cells/mm3

Public Health Service (US) releases updated guidelines for treatment of HIV positive pregnant women (April 2000)

French Health Authority approves enteric coated ddI

U.S. FDA approves film-coated nelfinavir mesylate (Viraceptâ„¢)

St John’s Wort

Volume 1 Number 1 April 2000 PDF

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