HTB

2000

Flavopiridol inhibits cellular processes essential to replication of HIV

Abbott expands early-access program for ABT-378/r (Kaletra)

Roche and Trimeris announce intention to manufacture commercial supplies of anti-HIV fusion inhibitor T-20

PRO-542 shows efficacy in trial

Immunorestitution disease

Prevalence of psoriatic arthritis increasing among HIV-positive black Zambians

HAART: enough to make your hair curl?

Loans to buy AIDS drugs are rejected by Africans

Volume 1 Number 6 September 2000 PDF

Severe Hypersensitivity Reactions following reintroduction with Ziagen (abacavir sulphate)

XIII International AIDS Conference, Durban, South Africa, 9-14th July 2000

Mother-to-child transmission, maternal health and women’s access to care

The M in MTCT: questions about HIV-positive mothers

First report of ABT-378/r use in children

Nelfinavir doses should be increased in infants less than 3 months

Metabolic and lipodystropy issues: confusion continues to reign

Switching studies: Can viral load be maintained and metabolic or fat redistribution significantly improved?

Commentary on STI talk, early entry inhibitor research, increase in viral replication seen in isolates in presence of NNRTIs

New developments in affordable antiretroviral therapy: intermittent treatment

Cannabinoids effect on HIV-1 viral load and appetite

IL-2 without HAART may delay need for antiretroviral treatment

New potential dual NNRTI-based combinations

Once-daily protease-based regimens

Mitochondrial DNA (mtDNA) damage in semen as surrogate marker for nucleoside analogue toxicity

Antiretrovirals and fertility – implications for couples looking to conceive

Incidence of adverse events at 4 weeks correlates with adherence and virologic failure at 4 months

Prednisone and nevirapine rash

The prevalence of hypogonadism in HIV positive patients receiving HAART

Human papilloma virus and HIV

$1bn drug deal creates debt for “tomorrow’s AIDS orphans”

Evaluating structured treatment interruptions: rationale, experience, potential risks and benefits

Maintenance of large numbers of virus-specific CD8+ T cells in HIV-infected progressors and long-term nonprogressors

European drug approvals: amprenavir, ddI EC, Trizivr and Kaletra

Volume 1 Number 5 August 2000 PDF

4th International Workshop on HIV Drug Resistance and Treatment Strategies, 12-16 June 2000, Sitges, Spain

Tenofovir (PMPA), defining cross-resistance profiles

DAPD shows activity in vitro against multidrug-resistant HIV but initial results from monotherapy in treatment experienced subjects are disappointing

Mycophenalate mofetil in patients with advanced disease and multidrug resistant HIV

Hydroxyurea is active in vitro against multidrug-resistant HIV

ABT-378/r (Lopinavir): defining a resistance profile and the effects of resistance on virological response in experienced patients

Indinavir/ritonavir at 400/400 mg or 800/100 mg as intensification

Ritonavir/saquinavir combination: effect of ritonavir dosage

What is the significance of blips in viral load?

Phenotypic resistance testing improves response to therapy: final analysis of VIRA3001

A prospective study of strategic treatment interruptions in patients with chronic HIV-infection

Added value of hydroxyurea or IL-2 to STIs remains uncertain

Continued benefits from protease inhibitor based therapy despite virological failure

Do resistance mutations disappear off therapy?

Selection of PI mutations during slow decay of VL and resistance after PI failure

Thymidine analogues mutations (TAMS) and other NA-related resistance mutations

Nevirapine vs efavirenz: the SENC trial

A warning on simplification strategies: not suitable for all

Prophylaxis and treatment of malaria in the presence of HIV protease inhibitor therapy

The 4th International AIDS Malignancy Conference

Accelerated replicative senescence of the peripheral immune system induced by HIV infection

Hit HIV-1 hard, but only when necessary

Gastrostomy tube (G-tube) insertion for improvement of adherence to HAART in pediatric patients with HIV

Study of amino acid methionine for treatment of myelopathy

3rd report of patient whose NRTI-associated lactic acidosis responded to riboflavin (vitamin B2)

Immune response may persist after emergence of protease inhibitor-resistant HIV

NIH suspends enrolment in Remune study

Nevirapine daily exposure for daily 400 mg dose compared to 200 mg twice-daily

Volume 1 Number 4 July 2000 PDF

Third International Workshop on Salvage Therapy for HIV Infection, April 12-14, 2000, Chicago, USA

Obiturary: Kiyoshi Kuromiya, 1943-2000

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