HTB

2010

Hepatitis B drugs in development

Hepatitis C treatment pipeline

Tuberculosis pipeline introduction

Tuberculosis diagnostic pipeline

Tuberculosis treatment pipeline

Tuberculosis vaccine pipeline

2010 pipeline report PDF

Volume 11 Number 5/6 May/June 2010

2nd Joint Conference of BHIVA with BASHH, 20–-23 April 2010, Manchester

HAART use among women in UK receiving treatment prior to conception

Duration of ruptured membranes and vertical transmission in the UK

Significant rates of unplanned pregnancies among young women born with HIV

Route of HCV transmission in HIV-positive gay men is unlikely to be from semen

75% HIV-positive children have insufficient levels of Vitamin D

Increase in LGV cases in gay men reported in the UK

High rates of osteopenia and osteoporosis: importance of DEXA monitoring

Summaries of other studies

11th International Workshop on Clinical Pharmacology of HIV Therapy, 7-9 April, 2010, Sorrento, Italy

Atazanavir absorption maximised with food

Methadone levels reduced moderately by rilpivirine

Maraviroc 150mg once-daily achieves target concentrations with atazanavir/ritonavir

Raltegravir and unboosted atazanavir

Raltegravir dose adjustment not required for patients on dialysis

Raltegravir and darunavir pharmacokinetics in liver disease

Tenofovir may require closer renal monitoring in older patients

Effect of age on atazanavir, darunavir, raltegravir and etravirine

Proposed approach to measuring TDM for raltegravir

Increased bilirubin levels when atazanavir is dosed twice-daily

17th Conference on Retroviruses and Opportunistic Infections (CROI) 16-19 February 2010, San Francisco

HIV reinfection cases reported at CROI

Hepatitis studies: IL28B genetics, HCV survival, FibroScan in acute HCV, MSM reinfection and responses to transplantation

Poor bioequivalence with crushed and dissolved tablets

Initial PK, safety and 12 week efficacy of raltegravir chewable tablets in children 6-11 years

PK of efavirenz in children dosed according to WHO weight bands

Virological and immunological responses in infants enrolled in the CHER trial

Darunavir-associated mutations in PI-naive and PI-experienced children in the UK

HIV persistence, raltegravir/maraviroc intensification and immunology

START study launched and endorsed by broad community support: over 140 community organisations sign letter to US guideline panel

FDA safety updates to antiretroviral labels

Development of apricitabine halted without finding backer for Phase 3

FDA approval of generic ARVs

U.S. government leading backlash against AIDS funding

Evidence from six countries confirms fears of People Living With HIV/AIDS: treatment rationing is escalating

Launch of the 10th funding round and other outcomes from the Global Fund

Pregnancy outcomes with efavirenz

The antiviral impact of CD8 T cells: much ado about the mechanism

Bad to the bone marrow?

Cell-free vs cell-associated HIV transmission

Coagulation and inflammatory biomarkers in children and adolescents with HIV

Pre-infection CD8 T cells targeting HIV linked to lower post-infection viral load

The HIV Research Catalyst Forum: treatment, prevention, advocacy

Experimental HCV drugs for HIV/HCV coinfected people: workshop on trial design

AIDS activists detained by Tanzanian authorities at World Economic Forum on Africa

China lifts travel ban on people with HIV

Malawian court’s 14-year sentence for gay men widely condemned

Uganda law proposes death penalty for homosexuality: can international reaction and vulnerability of treatment access programmes help?

Volume 11 Number 3/ May/April 2010 PDF

Volume 11 Number 3/4 March/April 2010

17th Conference on Retroviruses and Opportunistic Infections (CROI), 16-19 February 2010, San Francisco

Treatment reduces infections by over 90%: a theme that is here to stay

ACTG 5205: atazanavir/ritonavir vs efavirenz in treatment naive patients

Pipeline compounds and new approaches to treatment

Clinical benefits of stopping smoking: CVD and CHD risk returns to that of ‘previous smoker’ in HIV-positive people within three years

HIV increases the risk of lung cancer, independent of smoking status

HIV positive people in the HOPS cohort have 4-fold risk of fracture compared to general population in the US

Post navigation