HTB

2010

Vitamin D deficiencies in HIV management

OCTANE 2: nevirapine and lopinavir/r are similar when used with tenofovir and FTC in treatment-naive women

HIV incidence and retesting in pregnancy

Efavirenz use in pregnancy and birth outcomes

Pregnancy outcomes in women using non-AZT HAART in Europe

When should HAART be initiated in pregnancy to achieve an undetectable viral load?

Pregnancy outcomes in infants exposed to maternal antiretrovirals in utero

Maternal TB, HIV and pregnancy

Non-refrigerated ritonavir tablet approved in Europe and the US

FDA safety review of saquinavir (Invirase) and possible association with abnormal heart rhythms

FDA updates US label for darunavir (Prezista)

FDA safety announcement about ddI and non-cirrhotic portal hypertension

FDA label change for lopinavir/r (Kaletra)

FDA notice about drug interactions with etravirine (Intelence)

FDA approval of generic ARVs

Waiting lists grow in the US

South African antiretroviral treatment guidelines (2010)

Tenofovir registered in Russia

MSF criticise Abbott over new ritonavir formulation

BHIVA draft guidelines for the treatment of opportunistic infections (2010): online for comment

Infant feeding in the UK (2010): draft guidelines online for comment

Legal issues on HIV transmission and the law for healthcare workers: draft guidelines online for comment

Early predictors of disease progression

Sex and the single microbicide

Baseline naive CD4 T cell numbers predict the immunological response to ART

Has poor CD4 T cell reconstitution in the gut been exaggerated?

Journal articles

Volume 11 Number 3/4 March/April2010 PDF

CROI 2010: non technical summary of 12 key areas of research

CROI 2010: non-technical summary of 12 key areas of research PDF

Volume 11 Number 1/2 January/February2010

12th European AIDS Society Conference (EACS), 11-14 November 2009, Cologne

Screening for anal cancer recommended for HIV positive men

Once-daily darunavir/r monotherapy is suboptimal as initial regimen in treatment-naive people

Central fat accumulation remains a significant problem in patients starting HAART after 2005 with higher incidence in women compared to men

Alendronate improves bone mineral density in HIV positive people with osteoporosis at 96 weeks

TMC278 did not show teratogenic potential in animal models

Etravirine pregnancy data from five cases: no dose adjustment required

No clinically relevant interactions between TMC278 and oral contraceptives (norethindrone plus ethinylestradiol)

Gender-based differences in patients receiving antiretroviral therapy

Pilot PK study of two generic paediatric formulations of lopinavir/ritonavir vs originator products

Other selected PK and drug interaction summaries from EACS

11th International Workshop on Adverse Drug Reactions and Co-morbidities in HIV (IWADR) 26-28 October 2009, Philadelphia

The HCV pipeline – efficacy and side effect of compounds in Phase 3 studies

GSK issues Dear Doctor letter in the US: fosamprenavir and cardiovascular risk

HIV disease and renal function

Pregnancy not nevirapine associated with risk of hepatotoxicity in large cohort comparison

Birth defects following efavirenz exposure in a South African Hospital

Outcomes from screening study for anal cancer in HIV positive compared to HIV negative patients

No interaction between tipranavir/ritonavir and efavirenz

Significant interactions between tipranavir/ritonavir and statins

Summary of interactions between vivriviroc and other ARVs

Significant interaction between atazanavir/ritonavir and the antipsychotic drug quetiapine

US guidelines update (2010): treat when CD4 is less than 500 cells/mm3

WHO publish major revisions to HIV management guidelines (Nov 2009)

Updated paediatric HIV treatment guidelines (PENTA, 2009)

FDA approval of generic ARVs

UNITAID decision to fund ‘patent pool’ to boost access to new medicines

PEPFAR launches five-year strategy

Global Fund approves US$2.4 billion in new grants

Early predictors of disease progression

Bridging the neurology-immunology barrier

Free journal on immunology and cardiovascular disease

Male circumcision: new data supporting protective mechanism

A caution for male circumcision programmes: high complication rates highlighted outside a trial setting

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