FDA approves sofosbuvir/ledipasvir and sofosbuvir for children aged 12 to 17
26 June 2017. Related: Hepatitis coinfection, Paediatric care Comment
Comment
HIV Treatment Bulletin
Paediatric care
Community presentations: dental care, HIV awareness and access to formula milk
24 April 2017. Related: Conference reports, Paediatric care , BHIVA 23rd Liverpool 2017
VRC01 in HIV-exposed newborns: first results support monthly injections for those at risk through breastfeeding
24 April 2017. Related: Antiretrovirals, Conference reports, Paediatric care, PMTCT and maternal health , CROI 2017 (Retrovirus)
Raltegravir pharmacokinetic targets met in high-risk HIV-exposed infants
24 April 2017. Related: Antiretrovirals, Conference reports, Paediatric care, PK and drug interactions , CROI 2017 (Retrovirus)
Tenofovir alafenamide exposure is modestly higher in children than adults
24 April 2017. Related: Antiretrovirals, Conference reports, Paediatric care , CROI 2017 (Retrovirus)
New HIV diagnoses in children in UK and Ireland continue to decline
24 April 2017. Related: Conference reports, Diagnostics, Paediatric care, PK and drug interactions , CROI 2017 (Retrovirus)
World Health Organisation paediatric dosing tool
24 April 2017. Related: Conference reports, Paediatric care, PK and drug interactions , CROI 2017 (Retrovirus)
Dolutegravir exposure increases when fixed dose combination tablets are crushed
27 February 2017. Related: Antiretrovirals, Conference reports, Paediatric care , CROI 2017 (Retrovirus)
Pharmacokinetics, safety and efficacy of dolutegravir in very young children
27 February 2017. Related: Antiretrovirals, Conference reports, Paediatric care , CROI 2017 (Retrovirus)
FDA approves maraviroc for children aged two and older
29 November 2016. Related: Antiretrovirals, Paediatric care
Raltegravir-based third-line ART in children and adolescents
1 October 2016. Related: Antiretrovirals, Conference reports, Paediatric care , Global HIV Clinical Forum Durban 2016
Raltegravir in HIV-exposed neonates
1 October 2016. Related: Antiretrovirals, Conference reports, Paediatric care, PMTCT and maternal health , Paediatric Workshop 8 Durban 2016
Virological response without routine viral load monitoring in children: results from the ARROW trial
1 October 2016. Related: Conference reports, Paediatric care , Paediatric Workshop 8 Durban 2016
Tenofovir-containing ART reduces bone mineral density in breast feeding women: results from IMPAACT P1084s
1 October 2016. Related: Antiretrovirals, Conference reports, Paediatric care, PMTCT and maternal health , Paediatric Workshop 8 Durban 2016
PROMISE results support WHO recommendations for pregnant and breastfeeding women: more needs to be done to improve ART acceptability and adherence
1 August 2016. Related: Conference reports, Paediatric care, PMTCT and maternal health, Transmission and prevention , World AIDS 21 Durban 2016
No increased resistance with once daily dosing of abacavir and 3TC than twice daily dosing in the ARROW trial
1 August 2016. Related: Conference reports, Paediatric care, Resistance , Paediatric Workshop 8 Durban 2016
Shortened nine-month MDR-TB treatment works well in children and adolescents
1 August 2016. Related: Conference reports, Paediatric care, TB coinfection , TB 2016 Durban
Levofloxacin: safety and tolerability in HIV positive and negative children treated for MDR-TB
1 August 2016. Related: Conference reports, Paediatric care, TB coinfection , TB 2016 Durban
The paediatric antiretroviral pipeline
14 July 2016. Related: Antiretrovirals, Paediatric care, Pipeline report, Special reports
The paediatric tuberculosis treatment pipeline: beyond pharmacokinetics and safety data
14 July 2016. Related: Paediatric care, Pipeline report, Special reports, TB coinfection
No effect of tenofovir on infant bone mineral content in African study
1 June 2016. Related: Antiretrovirals, Conference reports, Paediatric care, PMTCT and maternal health , CROI 23 (Retrovirus) 2016
Use of modelling to predicting paediatric dosing of long acting antiretrovirals
1 June 2016. Related: Antiretrovirals, Conference reports, Paediatric care, PK and drug interactions , CROI 23 (Retrovirus) 2016
Nevirapine dosing for treatment of neonates
1 June 2016. Related: Conference reports, Paediatric care, PK and drug interactions , CROI 23 (Retrovirus) 2016
Dolutegravir: 48 week results in children age 6 to 12 years old
22 March 2016. Related: Conference reports, Paediatric care , CROI 23 (Retrovirus) 2016
Substituting lopinavir/ritonavir with efavirenz in children on stable ART
1 December 2015. Related: Antiretrovirals, Conference reports, Paediatric care , Paediatric Workshop 7 Vancouver 2015
The effects of systemic efavirenz exposure, sex and age on risk of viral non-suppression
1 December 2015. Related: Conference reports, Paediatric care, PK and drug interactions , Paediatric Workshop 7 Vancouver 2015
Pharmacokinetics of lopinavir/ritonavir super-boosting in infants and young children co-infected with HIV and TB
1 December 2015. Related: Conference reports, Paediatric care, PK and drug interactions, TB coinfection , Paediatric Workshop 7 Vancouver 2015
Protection against flu but not HBV in vaccinated perinatally HIV-infected children
1 October 2015. Related: Conference reports, Hepatitis coinfection, Paediatric care , ICAAC 55th San Diego 2015
Raltegravir for neonates will require a complicated dosing regimen
1 October 2015. Related: Conference reports, Paediatric care, PMTCT and maternal health
Paediatric dosing of DRV/r
1 October 2015. Related: Conference reports, Paediatric care, PK and drug interactions , PK Workshop 16th 2015
FDA approve additional weight band dosing for children using atazanavir powder
1 October 2015. Related: Antiretrovirals, Paediatric care
Dispersible tablet formulation of dolutegravir is bioequivalent to the granule formulation
1 August 2015. Related: Conference reports, Paediatric care , IAS 8 Vancouver 2015
The Pediatric Antiretroviral Pipeline
17 July 2015. Related: Antiretrovirals, Paediatric care, Pipeline report, Special reports
Momentum in the Pediatric Tuberculosis Treatment Pipeline
17 July 2015. Related: Paediatric care, Pipeline report, Special reports, TB coinfection
Other short reports from BHIVA:
1 June 2015. Related: Antiretrovirals, Basic science and immunology, Conference reports, Paediatric care , BHIVA 21st Brighton 2015
Elvitegravir in children and adolescents
1 June 2015. Related: Antiretrovirals, Conference reports, Paediatric care, PK and drug interactions , CROI 22 (Retrovirus) 2015
Point of care HIV PCR test for infant diagnosis: good performance but poorer results in youngest age group
24 March 2015. Related: Conference reports, Diagnostics, Paediatric care, PMTCT and maternal health , CROI 22 (Retrovirus) 2015
Weekend-off ART is non-inferior to continuous ART in young people taking efavirenz-based regimens: results from BREATHER study
24 March 2015. Related: Conference reports, Paediatric care, Treatment strategies , CROI 21 (Retrovirus) 2014
Increased cardiovascular risks in HIV positive children in Uganda and Zambia partially reversed by ART
24 March 2015. Related: Conference reports, Opportunistic infections and complications, Paediatric care , CROI 22 (Retrovirus) 2015
Lopinavir/ritonavir superior to nevirapine in children <3 years old: IMPAACT P1060 five year results
24 March 2015. Related: Conference reports, Paediatric care , CROI 22 (Retrovirus) 2015
Long-term safety and efficacy of tenofovir in children
24 March 2015. Related: Conference reports, Paediatric care , CROI 22 (Retrovirus) 2015
Drug resistance in children after PMTCT and early treatment
24 March 2015. Related: Conference reports, Paediatric care, PMTCT and maternal health, Resistance , idrw 24 Seattle 2015
Pharmacokinetics and safety of moxifloxacin in children
29 January 2015. Related: Conference reports, Paediatric care, PK and drug interactions , World Conference on Lung Health 45th 2014
TB in the ARROW trial of children on ART
29 January 2015. Related: Conference reports, Paediatric care, TB coinfection , World Conference on Lung Health 45th 2014
Problems giving current second line TB drugs to children
29 January 2015. Related: Conference reports, Paediatric care, TB coinfection , World Conference on Lung Health 45th 2014
Infants start ART too late but improvement over time in Southern Africa
1 December 2014. Related: Antiretrovirals, Conference reports, Paediatric care , Southern African Clinicians Society Conference 2014
Update on paediatric antiretrovirals
1 August 2014. Related: Antiretrovirals, Conference reports, Paediatric care , Paediatric Workshop 6 Melbourne 2014
Is d4T a viable option for children in low-income countries?
1 August 2014. Related: Antiretrovirals, Conference reports, Paediatric care , Paediatric Workshop 6 Melbourne 2014
3TC or FTC monotherapy suboptimal as a bridging strategy for adolescents
1 August 2014. Related: Conference reports, Paediatric care , Paediatric Workshop 6 Melbourne 2014
Rationalising the paediatric antiretroviral formulary in Malawi
1 August 2014. Related: Conference reports, Paediatric care, Treatment access , Paediatric Workshop 6 Melbourne 2014
Time to first-line failure in the IeDEA cohort
1 August 2014. Related: Conference reports, Paediatric care , Paediatric Workshop 6 Melbourne 2014
Influence of early ART on antibody detection in children
1 August 2014. Related: Conference reports, Paediatric care , Paediatric Workshop 6 Melbourne 2014
Wrestling with the implications of the Mississippi case
1 August 2014. Related: Cure research, Paediatric care
The paediatric antiretroviral pipeline
19 July 2014. Related: Antiretrovirals, Paediatric care, Pipeline report, Special reports
Playing catch-up: paediatric tuberculosis treatment pipeline
19 July 2014. Related: Paediatric care, Pipeline report, Special reports, TB coinfection
Once daily lopinavir/ritonavir not recommended for routine use in children and adolescents
27 May 2014. Related: Antiretrovirals, Conference reports, Paediatric care , CROI 21 (Retrovirus) 2014
Early antiretroviral treatment in infants
27 May 2014. Related: Antiretrovirals, Conference reports, Paediatric care , CROI 21 (Retrovirus) 2014
Catching up with pathogenesis and cure research from CROI 2014
27 May 2014. Related: Conference reports, Cure research, Paediatric care , CROI 21 (Retrovirus) 2014
Paediatric pipeline: CROI 2014 update on new antiretrovirals for children
24 March 2014. Related: Conference reports, Paediatric care , CROI 21 (Retrovirus) 2014
Efavirenz maintenance therapy effective in children exposed to nevirapine prophylaxis
24 March 2014. Related: Conference reports, Paediatric care , CROI 21 (Retrovirus) 2014
FDA approves raltegravir for children older than 4 weeks
24 March 2014. Related: Paediatric care
Lower immune response to the qHPV vaccine in HIV positive girls
1 February 2014. Related: Conference reports, Paediatric care, Women's health , Intl Workshop on HIV and Women 4th 2014
HIV exposed vs unexposed babies have lower gestational age and birth weight in Danish study
1 February 2014. Related: Conference reports, Paediatric care, PMTCT and maternal health , Intl Workshop on HIV and Women 4th 2014
Outcomes in infants exposed to lopinavir/ritonavir in utero
1 February 2014. Related: Antiretrovirals, Conference reports, Paediatric care, PMTCT and maternal health , Intl Workshop on HIV and Women 4th 2014
Preventing and treating TB in children – more baby steps
1 December 2013. Related: Conference reports, Paediatric care, PK and drug interactions, TB coinfection , World Conference on Lung Health 44th 2013