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Paediatric care

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• WHO paediatric recommendations Paediatric care - 5 February 2007

• Masking the flavour of antiretrovirals in Thai children Paediatric care - 5 February 2007

• Multi-drug resistance in vertically infected children Conference reports - Paediatric care - Resistance - HIV 8 Glasgow 2006 - 6 December 2006

• Wide disparity in switch to second-line therapy among children in CHIPS cohort Conference reports - Paediatric care - HIV 8 Glasgow 2006 - 6 December 2006

• US guidelines for the use of antiretroviral agents in paediatric HIV infection revised Guidelines - Paediatric care - 6 December 2006

• Children face a serious service delivery gap: paediatric studies in Toronto Conference reports - Paediatric care - World AIDS 16 Toronto 2006 - 9 September 2006

• Bioavailability study results for new paediatric tablets for oral suspension, and caution against splitting adult doses Conference reports - Paediatric care - World AIDS 16 Toronto 2006 - 9 September 2006

• Pharmacokinetic and virological evaluations after stopping NNRTIs in children: a substudy of the PENTA 11 (TICCH) Trial Conference reports - Paediatric care - World AIDS 16 Toronto 2006 - 9 September 2006

• 3TC/abacavir maintains virological superiority over AZT/3TC and AZT/abacavir beyond 5 years in children Conference reports - Paediatric care - World AIDS 16 Toronto 2006 - 9 September 2006

• Pharmacokinetics for generic fixed dose combinations for children are comparable to the branded products Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• Caution against dividing adult FDCs (Triomune) for young children Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• University of Liverpool audit of paediatric TDM Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• Age-dependent pharmacokinetics of 3TC in children Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• Use of small sample drug level monitoring for paediatric PI concentrations Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• Intracellular and plasma measurements of AZT and 3TC and their metabolites in neonates Conference reports - Paediatric care - PK Workshop 7th 2006 - 11 June 2006

• Once-daily FTC, ddI, and efavirenz in children and adolescents Conference reports - Paediatric care - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Simplified triple NRTI regimen effective in vertically infected children: two years follow-up Conference reports - Paediatric care - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Long-term clinical and biological outcomes in children vertically infected with HIV Conference reports - Paediatric care - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Prospective follow up of children with lipodystrophy Conference reports - Paediatric care - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Tuberculosis in HIV-positive children often missed from incidence data: the influence of HAART on paediatric TB Conference reports - Paediatric care - TB coinfection - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Nevirapine pharmacokinetics with infant prophylaxis Conference reports - Paediatric care - CROI 13 (Retrovirus) 2006 - 12 May 2006

• Paediatric studies at EACS: trends in antiretroviral use in the Madrid Cohort; life expectancy significantly increased HIV/HCV co-infected children since HAART; use of tenofovir in treatment experienced children; switching to lopinavir/r from double protease inhibitor regimen; once daily lopinavir/r, 3TC and abacavir; planned treatment interruptions in children Conference reports - Paediatric care - EACS 10 Dublin 2005 - 11 February 2006

• Comparison of pharmacokinetics of originator and generic liquid formulations and split tablets in Malawian children Conference reports - Paediatric care - ICAAC 45th Washingon 2005 - 10 February 2006

• US paediatric guidelines updated Guidelines - Paediatric care - 8 February 2006

• Pharmacokinetics of nevirapine in HIV positive children receiving Thai fixed dose combination Paediatric care - 13 October 2005

• Lopinavir/r use in children less than two years old – promising results despite low plasma levels Conference reports - Paediatric care - IAS 3 Rio de Janeiro 2005 - 14 September 2005

• Favourable outcomes in children treated with HAART in the MSF programmes Conference reports - Paediatric care - IAS 3 Rio de Janeiro 2005 - 14 September 2005

• Encouraging results with cut up generic fixed dose combination tablets in Uganda Conference reports - Paediatric care - IAS 3 Rio de Janeiro 2005 - 14 September 2005

• Predictors of survival at three years follow up for HIV-infected children in Cote D'Ivoire Conference reports - Paediatric care - IAS 3 Rio de Janeiro 2005 - 14 September 2005

• Underdosing of ARVs in children: results from CHIPS cohort Conference reports - Paediatric care - BHIVA 11th Dublin 2005 - 15 June 2005

• Dosing nevirapine in children Conference reports - Paediatric care - PK Workshop 6th 2005 - 15 June 2005

• Intracellular NRTI-triphosphate levels in children are similar to adults Conference reports - Paediatric care - PK Workshop 6th 2005 - 15 June 2005

• Once-daily lopinavir/ritonavir for children may offer advantages Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 15 May 2005

• Lopinavir/ritonavir for young infants Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 15 May 2005

• Paediatric dose finding atazanavir and atazanavir/ritonavir Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 15 May 2005

• Switching d4T to tenofovir and protease inhibitor to efavirenz Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 15 May 2005

• US guidelines on paediatric care updated Guidelines - Paediatric care - 15 May 2005

• Paediatric care in lower income settings Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 18 April 2005

• Tenofovir not linked to bone toxicity in children followed for one year Conference reports - Paediatric care - CROI 12 (Retrovirus) 2005 - 18 April 2005

• Higher nevirapine doses for children leads to better outcome Conference reports - Paediatric care - HIV 7 Glasgow 2004 - 29 March 2005

• Long-term response to FTC in children is similar to adults Conference reports - Paediatric care - ICAAC 44th Washington 2004 - 29 January 2005

• CHIPS data finds response to HAART varies with age in children Paediatric care - 6 November 2004

• HAART is effective in African children in a resource-limited setting Paediatric care - 6 November 2004

• Predictive factors of virologic success in HIV positive children treated with lopinavir/ritonavir Paediatric care - 6 November 2004

• Inventive ways to explain HAART and adherence to children Conference reports - Paediatric care - World AIDS 15 Bangkok 2004 - 6 September 2004

• Isoniazid has early and unexpected benefit in reducing childhood mortality Conference reports - Paediatric care - World AIDS 15 Bangkok 2004 - 6 September 2004

• Pharmacokinetic characteristics of ritonavir, zidovudine, lamivudine, and stavudine in children with HIV Paediatric care - 29 July 2004

• More positive children are surviving into adult life and require tailored services Conference reports - Paediatric care - BHIVA 10th Cardiff 2004 - 2 June 2004

• Higher nelfinavir concentrations improve response in children Conference reports - PK and drug interactions - Paediatric care - PK Workshop 5th 2004 - 2 May 2004

• PK of once daily lopinavir/r in children Conference reports - PK and drug interactions - Paediatric care - PK Workshop 5th 2004 - 2 May 2004

• Children’s HIV National Network (CHINN) Review Paediatric care - 2 May 2004

• FDA approves new paediatric dose of nelfinavir Paediatric care - 2 May 2004

• Tenofovir studies in children Conference reports - Paediatric care - CROI 11 (Retrovirus) 2004 - 2 April 2004

• Should treatment be started in all newborns infected with HIV? Paediatric care - 3 February 2004

• Tenofovir levels in children approach adult values Paediatric care - 3 February 2004

• Study suggests paediatric dose of emtricitabine (FTC) Paediatric care - 3 February 2004

• HIV production in children with “undetectable” viral load Paediatric care - 3 February 2004

• Host genetic factors are important in disease progression in children Paediatric care - 3 February 2004

• Dramatic decline in mortality, disease progression and hospital admissions in children with HIV infection in the UK and Ireland Paediatric care - 1 December 2003

• New tool for assessing risks of disease progression and death based on age, CD4 percentage and viral load in HIV-infected children Paediatric care - 1 December 2003

• Rituximab as single agent reversed paediatric Non-Hodgkins Lymphoma (NHL) Paediatric care - 1 November 2003

• Perinatal antiretroviral treatment and haematopoiesis in HIV-uninfected infants Paediatric care - 1 November 2003

• Higher than currently recommended NVP dose shows greater efficacy in HIV-infected children Paediatric care - 1 October 2003

• Nevirapine and MTCT: the single-dose backlash Antiretrovirals - Conference reports - PMTCT and maternal health - Paediatric care - Women's health - IAS 2 Paris 2003 - 1 September 2003

• Risk factors for paediatric HIV malignancies Cancer and HIV - Paediatric care - 1 July 2003

• TREC analysis shows little thymic damage in HIV-positive adolescents Paediatric care - 1 July 2003

• Metabolic abnormalities in protease inhibitor-treated and protease naïve children Lipodystrophy and metabolic complications - Paediatric care - 1 July 2003

• Paediatrics: neurological and developmental outcomes Conference reports - Opportunistic infections and complications - Paediatric care - BHIVA 9th Manchester 2003 - 1 June 2003

• Pediatric studies from 10th CROI Conference reports - PMTCT and maternal health - Paediatric care - Women's health - CROI 10 (Retrovirus) 2003 - 1 May 2003

• Adverse drug reactions and lipodystrophy in children Conference reports - Paediatric care - Side effects - ICAAC 42nd San Diego 2002 - 13 November 2002

• Antiretrovirals have neurologic benefits in children Paediatric care - 13 October 2002

• Early data highlight ribavirin's anti-adenovirus potential Paediatric care - 13 October 2002

• Four drug regimen for infants Conference reports - Paediatric care - World AIDS 14 Barcelona 2002 - 11 September 2002

• Emergence of resistance in children treated with ddI/d4T after treatment to reduce MTCT Conference reports - Paediatric care - World AIDS 14 Barcelona 2002 - 11 September 2002

• Increased risk of heart abnormalities in children born to mothers with HIV-1 Paediatric care - 11 September 2002

• Increased incidence of osteonecrosis of the hip observed in HIV-infected children Paediatric care - 11 July 2002

• CCR5 density on CD4 cells governs course of HIV infection in children Paediatric care - 11 June 2002

• Saquinavir is a suboptimal treatment for children unless used in combination Paediatric care - 11 June 2002

• Mothers, orphans, and prevention of paediatric AIDS PMTCT and maternal health - Paediatric care - 11 May 2002

• Birth defects linked to use of certain drugs during pregnancy Paediatric care - 10 January 2002

• Immune reconstitution in children treated with HAART is independent of age and pre-treatment immune status Paediatric care - 10 January 2002

• Lipodystrophy and metabolic changes in children Conference reports - Paediatric care - Lipodystrophy Workshop (IWADRLH) 3 Athens 2001 - 9 December 2001

• Syncytium inducing viral phenotype halves thymic T cell production in children Paediatric care - 9 December 2001

• Children with advanced disease who take HAART experience immune reconstitution Paediatric care - 9 December 2001

• EC approves abacavir for use by HIV-infected children Antiretrovirals - Paediatric care - 2 November 2001

• Puberty delayed in vertically infected children Paediatric care - 1 October 2001

• Metabolic abnormalities in children treated and not treated with protease inhibitors Paediatric care - 1 October 2001

• Protease inhibitor therapy improves growth parameters of HIV-infected children Paediatric care - 30 June 2001

• Antiretroviral therapy improves measles vaccination response in HIV-infected children Paediatric care - 17 May 2001

• Paediatric treatment issues at the 8th CROI Conference reports - Paediatric care - Resistance - CROI 8 (Retrovirus) 2001 - 17 April 2001

• Efavirenz use in HIV-positive children Antiretrovirals - Paediatric care - 17 April 2001

• Steatorrhea prevalent in HIV-positive children; clinical significance unclear Paediatric care - 17 April 2001

• Effective antiretroviral therapy resolves HIV organ-specific complications in 3 children Paediatric care - 17 March 2001

• Medication adherence poor for many HIV-infected children Paediatric care - 17 January 2001

• Oral ganciclovir safe, effective for children co-infected with CMV and HIV Opportunistic infections and complications - Paediatric care - 17 January 2001

• High cancer incidence in perinatally HIV-infected children Cancer and HIV - Paediatric care - 17 January 2001

• Functional aerobic impairment detected in HIV-seropositive teens Paediatric care - 17 January 2001

• Most untreated African HIV children will die by age 3 Paediatric care - 17 January 2001

• Antiretroviral therapy in children, women and intravenous drug users Conference reports - Paediatric care - Women's health - HIV 5 Glasgow 2000 - 17 December 2000

• Lipodystrophy and metabolic changes in children Conference reports - Paediatric care - Lipodystrophy Workshop (IWADRLH) 2 Toronto 2000 - 17 October 2000

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