HTB

2006

FDA decision delayed on Biojector for administering T-20 pending additional safety information

BHIVA draft report on UK standards for HIV care (2006)

US adult treatment guidelines updated (2006)

Gilead licenses tenofovir to Indian generic manufacturers

Funding prospects improve for Round 6 Global Fund

Extensively drug resistant tuberculosis: a serious wake-up call for global health

Global report on TB and HIV: new analysis of TB/HIV epidemics in Bangladesh, Brazil, Nigeria, Tanzania, and Thailand

Viral load is a poor predictor of CD4 decline at the individual level

Volume 7 Number 10 October 2006 PDF

Volume 7 Number 9 September 2006

XVI International AIDS Conference, Toronto, Canada. 13-18 August 2006

Enough is enough: South African activists demand: fire Manto

Treatment access: more optimistic results from scale up programmes

Integrase inhibitor MK-0518: early results show greater early potency than efavirenz

Maraviroc results in R5/X4 mixed/dual tropic patients: unexpected safety data shows possible immunolocical effect

Vicriviroc 24-week results in triple-class experienced R5-tropic patients

Etravirine (TMC-125) associated with -1 log viral load reduction at 48-weeks results in treatment experienced patients

Three-class experienced patients experience 1 log viral load reduction using monoclonal antibody TNX-355

New data on darunavir (TMC-114)

Lopinavir/r monotherapy: less potent than triple therapy with higher risk of resistance

Atazanavir/r monotherapy and CNS penetration

Fosamprenavir/r is non-inferior to Kaletra in treatment naive patients

Tenofovir/FTC maintains greater virological response and reduced lipoatrophy compared to AZT/3TC after 96 weeks

Children face a serious service delivery gap: paediatric studies in Toronto

Bioavailability study results for new paediatric tablets for oral suspension, and caution against splitting adult doses

Pharmacokinetic and virological evaluations after stopping NNRTIs in children: a substudy of the PENTA 11 (TICCH) Trial

3TC/abacavir maintains virological superiority over AZT/3TC and AZT/abacavir beyond 5 years in children

French study raises importance of early screening for anal cancer in HIV-positive people

Prognostic index for risk of progression of Kaposi’s Sarcoma

Tenofovir did not increase the incidence nephrotoxicity in limited numbers of HIV-positive patients using chemotherapy or HCV-coinfeced patients using ribavirin

Selected abstracts from Track A presentations at Toronto

Use of complementary alternative medicine that could interact with ARV treatment reported by 20% patients in the UK

Poor scientific or medical knowledge is a factor in increase in criminal charges for HIV transmission in the UK

Treatment access and community responses: online webcasts and debates

Patent oppositions filed on three essential drugs

WHO guidelines for ARV treatment in resource limited settings (2006)

Antiretroviral effect of foscarnet in patients with multiple drug resistance in late stage HIV disease

AIDS issue of the British medical journal The Lancet online

TAG pipeline drugs report: July 2006

OSI/TAG report on civil society involvement in TB/HIV

Tuberculosis R&D Investments: A Preliminary Assessment

Resource for HIV-positive travellers: HIV/AIDS regulations

Volume 7 Number 9 September 2006 PDF

Volume 7 Number 7/8 July/August 2006

Dear Doctor letter issued in the U.S. relating to 14 reports of intracranial haemorrhage (ICH) events with tipranavir/r

15th International Drug Resistance Workshop, 13-17 June 2006, Sitges, Spain

Resistance implications of monotherapy with lopinavir/r (Kaletra)

Ritonavir reduces virological failure and resistance in treatment naive patients treated with atazanavir

Resistance to darunavir (TMC-114): predicting responses for treatment experienced patients

Epidemiological studies and transmission of resistance: evidence for optimism – or issues with interpretation?

K103N containing variants persist longer in women with subtype D and with higher viral loads

No subtype-based differences in baseline levels of K103N-containing variants in women receiving single dose nevirapine

Phenotypic NNRTI resistance and genetic diversity in antiretroviral naive women

High prevalence of the K65R mutation in Botswana patients treated with ddI/d4T-based regimens

Potential for easier selection of K65R mutation with tenofovir pressure in subtype C HIV-1 isolates

Categorisation of transmitted HIV drug resistance using the WHO/CDC HIV drug resistance threshold survey method may be useful in resource limited settings

Limitations in online tools to identify HIV-1 subtypes

Resistance implications from PrEP and microbicide studies in macaques

Low-level resistance linked to treatment failure: a role for more sensitive testing for naive patients

Testing for resistance after starting treatment

New formulation of lopinavir/r approved in Europe (Kaletra) and new tradename for access countries (Aluvia)

US approval for darunavir (TMC-114, Prezista)

Boehringer stops tipranavir trial in treatment-naive patients

FDA approves fixed-dose combination of efavirenz/tenofovir/FTC (Atripla): joint company collaboration produces once-daily one pill combination

Evidence that CCR5 is protective against West Nile virus: implications for CCR5 inhibitors

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