HTB

2019

Other cure related studies at CROI 2019

Dual long-acting cabotegravir/rilpivirine injection submitted to FDA

Dolutegravir/3TC dual FDC (Dovato) approved in the US and given positive opinion in the EU

King’s launches transgender sexual health service with cliniQ

30 April 2019 vol 20 no 5

29 March 2019: vol 20 no 4 – second CROI reports

Conference on Retroviruses and Opportunistic Infections (CROI 2019): second reports

Maturation inhibitor GSK’232 reduces viral load by –1.5 log at day 10

Capsid inhibitor GS-6207 shows potential for 3-monthly injections

First phase 1 results from bNAb PGT121 in HIV positive people

Dolutegravir/3TC dual ART is as effective at lowest viral load cut-off as triple therapy in GEMINI studies

Same-day ART is effective in San Francisco Rapid-ART clinic

Integrase inhibitors and neural tube defects: more data still needed

Double-dose levonorgestrel implant does not overcome interaction with efavirenz

Efavirenz and rifampicin together reduce levels of injectable contraception

Bedaquiline and delamanid safe when given together to treat drug resistant TB

Isoniazid preventative therapy in HIV positive pregnant women not linked to poor outcomes

Dear Doctor letter: Increased risk of treatment failure and increased risk of mother-to-child transmission of HIV infection dues to lower exposure of elvitegravir and cobicistat during the second and third trimesters of pregnancy

29 March 2019 vol 20 no 4

13 March 2019: vol 20 no 3 – first CROI reports

Conference on Retroviruses and Opportunistic Infections (CROI 2019): early reports

UK patient likely to be the second person cured of HIV: two further cases at CROI 2019 of HIV remission after allogenic stem cell transplants

Phase 3 results with dual therapy cabotegravir/rilpivirine long-acting injections: ATLAS and FLAIR studies

Viral reservoir can explain persistent low level viraemia with good adherence on ART

Dolutegravir suppresses viral load faster than efavirenz in late pregnancy: results from DolPHIN-2

Raltegravir achieves swifter viral load suppression in pregnancy than efavirenz

New option for PrEP – TAF/FTC is non-inferior to TDF/FTC: results of phase 3 DISCOVER study

Dolutegravir can be given with 3HP to prevent TB without dose adjustment

Double doses of darunavir given with rifampicin lead to high rates of hepatoxicity

Shared housing compared to living alone: higher CD4, lower viral load and reduced inflammation in macaques

Selected webcasts at CROI 2019

i-Base Fit for Purpose report launched at CROI 2019

Pre-CROI Community HIV Cure Workshop 2019

US requires informed consent forms for clinical studies to be posted online

Reports from cure strategies meetings

13 March 2019 vol 20 no 3

22 February 2019: vol 20 no 2 – remembering Mags…

27th International Workshop on HIV Drug Resistance and Treatment Strategies

Drug resistance in low- and middle-income countries

Remembering Dr Mags Portman: pioneer activist for sexual health

BHIVA guidelines for adult TB/HIV coinfection (2018)

UK BHIVA pregnancy guidelines updated (2018)

Regular marijuana smoking linked to lung disease in HIV positive but not HIV negative men

Civil society organisations push for a target of $18 billion for the Global Fund’s sixth replenishment

Arabic translation of U=U factsheet

Recent papers from the Swiss HIV Cohort Study newsletter

Fit for the Future: NHS long-term plan explained

22 February 2019 vol 20 no 2

21 January 2019: vol 20 no 1: Brexit and other complications…

BMJ survey reports lack of NHS planning for Brexit: impact on drug supplies unknown

BASHH, BHIVA, HIVPA and NHIVNA statement on a no-deal Brexit

UK-CAB statement on Brexit, HIV and access to medicines

Model predicts benefit of dolutegravir for all in sub-Saharan Africa outweighs risk

Are integrase inhibitors linked to weight gain? – an evidence review

HIV is associated with higher biological age compared to chronological age

Frailty in older HIV positive people: independent associations with serious morbidity and mortality

US adult HIV guidelines updated (Oct 2018)

NHS England doubles places on IMPACT PrEP study to 26,000

US CDC updates HIV rates in transgender people

UK annual HIV surveillance data published – full reports

Michigan State updates HIV disclosure laws to reflect impact of effective ART

Conference abstracts online

Chemsex: online resources

TAGline: Intellectual Property and Access

Activists announce alternative 2020 conference in Mexico City

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