HTB

Conference reports

Daily oral tenofovir/FTC PrEP reduces heterosexual transmission by 63% in the TDF2 study

Tenofovir/FTC vs tenofovir as daily oral PrEP: preliminary results from Partners PrEP

Elvitegravir vs raltegravir: 48 week results in treatment-experienced patients

Dolutegravir: 48 week results from phase II study in treatment-naive patients

Lersivirine: 48 week results compared to efavirenz in phase 2 treatment-naive study

Maraviroc plus atazanavir/r without nukes versus standard of care: 48 week results

SPARTAC trial: treatment in primary infection for 48 weeks shows small delay in disease progression

Hearing loss not associated with HIV in MACS and WIHS cohorts

Pharmacokinetics of darunavir and fosamprenavir in pregnancy

Low birth weight and preterm delivery

Hormonal contraception and HIV transmission risk

No difference in AIDS-free survival in children starting ART with a CD4% between 15%–24% compared to deferring until less than 15% in the PREDICT trial

Paediatric antiretroviral pipeline: update on etravirine and maraviroc

Prematurity not associated with early mortality in infants on ART

More metabolic abnormalities in children receiving a PI compared to NNRTI in NEVEREST study

Free online resource for treatment decisions without access to genotype resistance tests

17th Annual Conference of the British HIV Association (BHIVA) 6-8 April 2011, Bournemouth

Treatment in seroconversion maintains HIV specific immune responses similar to long term slow progressors

18th Conference on Retroviruses and Opportunistic Infections (CROI) 27 February-–3 March 2011, Boston

Monitoring treatment in resource limited settings: results from PHPT-3 and Stratall ANRS12110/ESTER trials

DART: high rates of viral suppression after five years and a single CD4 test with a threshold of 250 cells/mm3 could reduce unnecessary switching

Lopinavir/r monotherapy used as second-line therapy in resource-limited settings

Treating children previously exposed to single dose nevirapine: update on IMPAACT P1060 and NEVEREST

Lopinavir/ritonavir oral solution toxicity in neonates

Paediatric antiretroviral pipeline: darunavir and raltegravir

Pharmacokinetics of different rifabutin dosing strategies with lopinavir/ritonavir-based ART

Initiation of ART during breastfeeding can induce multidrug resistance in infants

First Workshop on Nanomedicine for Infectious Diseases of Poverty, 27-31 March 2011, Magaliesberg, South Africa

17th Annual Conference of the British HIV Association (BHIVA), 6-8 April 2011, Bournemouth

Atazanavir in pregnancy: 155 cases in London clinics

Co-morbidity and late presentation – findings from an over 50s cohort

Health outcomes for young adults with perinatally acquired HIV infection following transfer to adult services

The use of calcaneal stiffness index to screen for osteoporosis in HIV-infected individuals

Frequency and characteristics of long-term non-progressors and HIV controllers in the Chelsea and Westminster cohort

Cerebral function in perinatally HIV infected young people and HIV uninfected sibling controls

An audit of HIV care provision for Immigration Removal Centre patients

12th International Workshop on Clinical Pharmacology of HIV Therapy, 13–-15 April 2011, Miami

Quad reduces levels of oral contraceptives

Elvitegravir/cobicistat and acid reducing agents

Lopinavir/r reduces levels of rifabutin

Cobicistat has little impact on CYP2D6 and CYP2B6

Atazanavir levels indicate need for higher dose during pregnancy

Etravirine lowers levels of maraviroc given at 300 or 600 mg twice daily

Once-daily 150-mg maraviroc explored in people taking atazanavir/ritonavir

Lopinavir troughs lower in children on once-daily dose with efavirenz

Dose optimisation: 50 mg ritonavir-boosting, 3TC dosing and raltegravir once-daily

46th European Association for the Study of the Liver (EASL), 30 March-3 April 2011, Berlin, Germany

Rapid report: state of HCV policy, treatment, access

18th Conference on Retroviruses and Opportunistic Infections (CROI), 27 February–-3 March 2011, Boston

When to start ART in patients co-infected with TB: results from two trials presented at CROI

Inflammation and intervention: how does HIV cause AIDS and how does it cause disease despite ART

18th Conference on Retroviruses and Opportunistic Infections (CROI), 27 February-–3 March 2011, Boston

New antiretrovirals: dolutegravir, entry inhibitor (BMS-663068) and tenofovir pro-drug (GS-7340)

Immune-based treatment increases HIV-resistant CD4 cells in phase 1 study

Antiretroviral prevention: oral PrEP, gels and treatment studies

Further efficacy analyses from the iPrEx study

Topical gels as PEP and PrEP: animal and human studies

Maternal risk following short course HAART

Pre-term delivery and HAART

HAART more effective than AZT monotherapy in the Botswana PMTCT programme

Lopinavir/r monotherapy for PMTCT

No evidence of increased risk of MTCT with sequential pregnancies in UK and Ireland

Recently infected women at the time of delivery have a higher rate of in-utero transmission in PEPI-Malawi

Reduced CCL22 concentrations in cervicovaginal secretions from pregnant women

First results from telaprevir in HIV/HCV coinfection

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