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Conference reports

Recombination dynamics in case of MDR sub-type D following superinfection with wild-type sub-type B

Defective viral reservoir populations is common in patients on long-term suppressed ART

First case report of transmission with five-class resistance

New data on the Berlin patient: interpret with caution

18th Annual BHIVA Conference, 18-20 April 2012, UK

Half of gay men in London would chose oral PrEP to reduce risk of HIV

Recent infection is common in UK; 30% gay men aged 15-25 infected within a year of diagnosis

One third of HIV positive people at five UK clinics have symptomatic depression: link to adherence and viral suppression – 40% cases are untreated

Hodgkin’s lymphoma: survival normalises to HIV negative rates despite more advanced disease at diagnosis

Promising outcomes from laser ablative treatment of AIN2/3 to prevent anal cancer

KS in the HAART era includes patients with high CD4 and suppressed viral load: importance of KS chemotherapy for some patients in addition to ART

3rd vs 4th generation HIV testing: almost half of UK clinics out of step with national guidelines

Case reports of complications from ketamine use in two MSM on ritonavir-based combinations

Intranasal and topical corticosteroids and risk of Cushing’s symptoms in HIV patients on ritonavir-based combinations

Outcomes from switches to atazanavir/r in London

Intimate partner violence towards HIV positive women in the UK

13th International workshop on Clinical Pharmacology of HIV Therapy, 16-18 April 2012, Barcelona

Studies on pipeline ARVs

Washout pharmacokinetics of transplacental raltegravir in neonates

Interactions between malaria drugs and etravirine or darunavir/r

No interaction between antimalarial amodiaquine and nevirapine

Pharmacokinetics of atazanavir/ritonavir plus raltegravir

Atazanavir/ritonavir and voriconazole not to be coadministered

Milk thistle (silymarin) and darunavir/ritonavir

Echinacea and etravirine

Warfarin and ARVs: impact of African American race and ritonavir

19th Conference on Retroviruses and Opportunistic Infections (CROI), 5-8 March 2012, Seattle

HIV and the brain: longitudinal results from CHARTER and other studies

Systolic blood pressure and risk of myocardial infarction in HIV infection

Risk of non-AIDS defining malignancies and immune suppression

Renal impairment in the D:A:D study

Early data for rilpivirine long acting formulation supports further investigation for PrEP

Hormonal contraception: HIV transmission and progression rates

Darunavir use during pregnancy

19th Conference on Retroviruses and Opportunistic Infections (CROI), 5-8 March 2012

Cure research takes centre stage: proof of concept for activating the latent reservoir

Quad fixed-dose integrase combination: phase 3 studies at week 48

Dolutegravir studies continue to show promise

Tenofovir prodrug: 10 day monotherapy study sets dose at 25 mg for easier coformulation

Paediatric formulations of ARVs: including an exciting new class

Lower malaria risk in children receiving lopinavir/ritonavir-based compared to NNRTI-based ART

High prevalence of d4T-associated lipodystrophy including lipoatrophy in children

Lopinavir/ritonavir monotherapy in children

Stopping treatment after early ART in infants

PrEP: PK modeling of daily TDF/FTC (Truvada) provides close to 100% protection against HIV infection

Risk of HIV reinfection may be similar to risk of initial HIV infection

Case report: homozygous CCR5 delta-32 protection overcome by infection with X4 virus

No association between atazanavir and MI or stroke in D:A:D study

Hepatitis C coinfection studies

Herpes Zoster vaccine safe and effective in HIV positive people

High dose flu vaccine improves antibody responses in HIV positive people

2nd International Workshop on HIV & Women, 9-10 January 2012, Bethesda, USA

Similar efficacy and a few gender related differences in side effects with rilpivirine vs efavirenz at 96-weeks

The effect of BMI on efficacy, safety and tolerability of lopinavir/r in women

Hormonal contraception and higher risk of non-AIDS-defining events in Nashville cohort

Poorer adherence and loss to follow up in Kenyan women who are pregnant when enrolled to ART programmes

5th HIV Persistence Workshop on HIV Reservoirs, 6-9 December 2011, West Indies

Workshop report and commentary: HIV persistence and reservoirs

13th European AIDS Conference (EACS), Belgrade, Serbia, 12-15 October 2011

European guidelines (EACS) – 2011 update

Raltegravir achieves superiority over efavirenz after four years

Higher plasma levels of tenofovir and darunavir but not efavirenz in older patients

Ritonavir levels reduced with high fat meal

Transplacental transfer of raltegravir and delayed plasma clearance in preterm neonates

2nd International Workshop on HIV and Ageing, Baltimore, Maryland, 27-28 October 2011

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