Darunavir use during pregnancy
1 June 2012. Related: Conference reports, Antiretrovirals, Women's health, Pregnancy, PK and drug interactions.
Conference reports
19th Conference on Retroviruses and Opportunistic Infections (CROI), 5-8 March 2012
1 April 2012. Related: Conference reports.
Cure research takes centre stage: proof of concept for activating the latent reservoir
1 April 2012. Related: Conference reports, Cure-related research, Basic science and immunology.
Quad fixed-dose integrase combination: phase 3 studies at week 48
1 April 2012. Related: Conference reports, Antiretrovirals.
Dolutegravir studies continue to show promise
1 April 2012. Related: Conference reports, Antiretrovirals, Pregnancy.
Tenofovir prodrug: 10 day monotherapy study sets dose at 25 mg for easier coformulation
1 April 2012. Related: Conference reports, Antiretrovirals.
Paediatric formulations of ARVs: including an exciting new class
1 April 2012. Related: Conference reports, Antiretrovirals, Paediatric care.
Lower malaria risk in children receiving lopinavir/ritonavir-based compared to NNRTI-based ART
1 April 2012. Related: Conference reports, Paediatric care.
High prevalence of d4T-associated lipodystrophy including lipoatrophy in children
1 April 2012. Related: Conference reports, Antiretrovirals, Paediatric care.
Lopinavir/ritonavir monotherapy in children
1 April 2012. Related: Conference reports, Paediatric care.
Stopping treatment after early ART in infants
1 April 2012. Related: Conference reports, Paediatric care.
PrEP: PK modeling of daily TDF/FTC (Truvada) provides close to 100% protection against HIV infection
1 April 2012. Related: Conference reports, HIV prevention and transmission.
Risk of HIV reinfection may be similar to risk of initial HIV infection
1 April 2012. Related: Conference reports, HIV prevention and transmission.
Case report: homozygous CCR5 delta-32 protection overcome by infection with X4 virus
1 April 2012. Related: Conference reports, HIV prevention and transmission.
No association between atazanavir and MI or stroke in D:A:D study
1 April 2012. Related: Conference reports, Side effects, Coinfections and complications.
Hepatitis C coinfection studies
1 April 2012. Related: Conference reports, Hepatitis coinfection.
Herpes Zoster vaccine safe and effective in HIV positive people
1 April 2012. Related: Conference reports, Vaccines and microbicides.
High dose flu vaccine improves antibody responses in HIV positive people
1 April 2012. Related: Conference reports, Vaccines and microbicides.
2nd International Workshop on HIV & Women, 9-10 January 2012, Bethesda, USA
1 February 2012. Related: Conference reports.
Similar efficacy and a few gender related differences in side effects with rilpivirine vs efavirenz at 96-weeks
1 February 2012. Related: Conference reports, Antiretrovirals, Pregnancy.
The effect of BMI on efficacy, safety and tolerability of lopinavir/r in women
1 February 2012. Related: Conference reports, Antiretrovirals, Women's health.
Hormonal contraception and higher risk of non-AIDS-defining events in Nashville cohort
1 February 2012. Related: Conference reports, Women's health.
Poorer adherence and loss to follow up in Kenyan women who are pregnant when enrolled to ART programmes
1 February 2012. Related: Conference reports, Antiretrovirals, Pregnancy.
5th HIV Persistence Workshop on HIV Reservoirs, 6-9 December 2011, West Indies
1 February 2012. Related: Conference reports, Cure-related research, Basic science and immunology, Virology.
Workshop report and commentary: HIV persistence and reservoirs
1 February 2012. Related: Conference reports, Cure-related research, Basic science and immunology, Virology.
13th European AIDS Conference (EACS), Belgrade, Serbia, 12-15 October 2011
1 December 2011. Related: Conference reports.
European guidelines (EACS) – 2011 update
1 December 2011. Related: Conference reports, Guidelines.
Raltegravir achieves superiority over efavirenz after four years
1 December 2011. Related: Conference reports, Antiretrovirals.
Higher plasma levels of tenofovir and darunavir but not efavirenz in older patients
1 December 2011. Related: Conference reports, PK and drug interactions.
Ritonavir levels reduced with high fat meal
1 December 2011. Related: Conference reports, PK and drug interactions, Nutrition.
Transplacental transfer of raltegravir and delayed plasma clearance in preterm neonates
1 December 2011. Related: Conference reports, Pregnancy.
2nd International Workshop on HIV and Ageing, Baltimore, Maryland, 27-28 October 2011
1 December 2011. Related: Conference reports.
Statin blocks negative impact of PIs on bone formation in vitro
1 December 2011. Related: Conference reports, Antiretrovirals.
HIV linked to frailty in middle-aged IDUs, especially with poor HIV control
1 December 2011. Related: Conference reports, Coinfections and complications.
51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Chicago, 17-20 September 2011
1 December 2011. Related: Conference reports.
Monitoring kidney function change with cobicistat
1 December 2011. Related: Conference reports, PK and drug interactions.
Intracellular raltegravir concentrations better with twice-daily than once-daily dosing
1 December 2011. Related: Conference reports, Antiretrovirals.
6th IAS Conference on HIV Pathogenesis, Treatment and Prevention, 17-20 July 2011, Rome
1 October 2011. Related: Conference reports.
Cure research and viral reservoirs
1 October 2011. Related: Conference reports, Cure-related research, Basic science and immunology.
Orange Farm circumcision results dispel concerns about risk compensation
1 October 2011. Related: Conference reports, HIV prevention and transmission.
Randomised trial of ART in TB patients with high CD4 counts
1 October 2011. Related: Conference reports, TB coinfection.
6th IAS Conference on HIV Pathogenesis, Treatment and Prevention 17-20 July 2011, Rome
1 August 2011. Related: Conference reports.
Webcasts for major research at IAS
1 August 2011. Related: Conference reports.
Treatment is prevention: ARV treatment in HPTN-052 reduces transmission by at least 96%: single transmission in treatment arm occurred before viral suppression
1 August 2011. Related: Conference reports, Antiretrovirals, HIV prevention and transmission.
Daily oral tenofovir/FTC PrEP reduces heterosexual transmission by 63% in the TDF2 study
1 August 2011. Related: Conference reports, Antiretrovirals, HIV prevention and transmission.
Tenofovir/FTC vs tenofovir as daily oral PrEP: preliminary results from Partners PrEP
1 August 2011. Related: Conference reports, Antiretrovirals, HIV prevention and transmission.
Elvitegravir vs raltegravir: 48 week results in treatment-experienced patients
1 August 2011. Related: Conference reports, Antiretrovirals.
Dolutegravir: 48 week results from phase II study in treatment-naive patients
1 August 2011. Related: Conference reports, Antiretrovirals.
Lersivirine: 48 week results compared to efavirenz in phase 2 treatment-naive study
1 August 2011. Related: Conference reports, Antiretrovirals.
Maraviroc plus atazanavir/r without nukes versus standard of care: 48 week results
1 August 2011. Related: Conference reports, Antiretrovirals.
SPARTAC trial: treatment in primary infection for 48 weeks shows small delay in disease progression
1 August 2011. Related: Conference reports, Antiretrovirals.
Hearing loss not associated with HIV in MACS and WIHS cohorts
1 August 2011. Related: Conference reports, Side effects, Coinfections and complications.
Pharmacokinetics of darunavir and fosamprenavir in pregnancy
1 August 2011. Related: Conference reports, Pregnancy, PK and drug interactions.
Low birth weight and preterm delivery
1 August 2011. Related: Conference reports, Pregnancy.
Hormonal contraception and HIV transmission risk
1 August 2011. Related: Conference reports, Pregnancy.
No difference in AIDS-free survival in children starting ART with a CD4% between 15%24% compared to deferring until less than 15% in the PREDICT trial
1 August 2011. Related: Conference reports, Paediatric care.
Paediatric antiretroviral pipeline: update on etravirine and maraviroc
1 August 2011. Related: Conference reports, Paediatric care.
Prematurity not associated with early mortality in infants on ART
1 August 2011. Related: Conference reports, Paediatric care.
More metabolic abnormalities in children receiving a PI compared to NNRTI in NEVEREST study
1 August 2011. Related: Conference reports, Paediatric care, Side effects.
Free online resource for treatment decisions without access to genotype resistance tests
1 August 2011. Related: Conference reports, Drug resistance.
17th Annual Conference of the British HIV Association (BHIVA) 6-8 April 2011, Bournemouth
1 August 2011. Related: Conference reports.
Treatment in seroconversion maintains HIV specific immune responses similar to long term slow progressors
1 August 2011. Related: Conference reports, Treatment strategies, Basic science and immunology.
18th Conference on Retroviruses and Opportunistic Infections (CROI) 27 February-3 March 2011, Boston
1 August 2011. Related: Conference reports.
Monitoring treatment in resource limited settings: results from PHPT-3 and Stratall ANRS12110/ESTER trials
1 August 2011. Related: Conference reports, Treatment strategies, Treatment access.
DART: high rates of viral suppression after five years and a single CD4 test with a threshold of 250 cells/mm3 could reduce unnecessary switching
1 August 2011. Related: Conference reports, Treatment strategies, Treatment access.