Conference reports

13 November 2018. Related: Conference reports, Antiretrovirals.

3D imaging show HIV infection might establish within hours

13 November 2018. Related: Conference reports, HIV prevention and transmission.

bNAbs for HIV prevention: extended-release VRC01, AMP study, 10E8 safety signal and pan-clade challenges

13 November 2018. Related: Conference reports, PK and drug interactions, HIV prevention and transmission.

Why U=U does not cover breastfeeding

13 November 2018. Related: Conference reports, Paediatric care.

BHIVA Autumn Conference 2018

19 October 2018. Related: Conference reports.

Second case of potential HIV eradication

19 October 2018. Related: Conference reports, Cure-related research.

New UK PrEP guidelines 2018

19 October 2018. Related: Conference reports, HIV prevention and transmission.

Other selected talks at BHIVA Autumn 2018

19 October 2018. Related: Conference reports.

9th International Workshop on HIV and Ageing

19 October 2018. Related: Conference reports, Lipodystrophy and metabolic complications, Coinfections and complications.

Detectable viral load quadruples odds of recurrent falls in older men with HIV

19 October 2018. Related: Conference reports, Coinfections and complications.

More than 40% of HIV group has hepatic steatosis, regardless of age

19 October 2018. Related: Conference reports, Coinfections and complications.

Associations of loneliness with cognitive function and quality of life (QoL) among older adults living with HIV – 18% lonely quite often

19 October 2018. Related: Conference reports, Coinfections and complications.

Physical function worse in older women than men with HIV, despite better CD4 recovery

19 October 2018. Related: Conference reports, Coinfections and complications.

22nd International AIDS Conference (AIDS 2018) – third reports

19 September 2018. Related: Conference reports.

Dolutegravir twice daily is effective and tolerable with rifampicin: 48 week results from the INSPIRING study

19 September 2018. Related: Conference reports, TB coinfection.

TAF exposures during pregnancy and postpartum appear adequate but more data are needed

19 September 2018. Related: Conference reports, Pregnancy.

High rate of unintended pregnancy among HIV positive African women on ART

19 September 2018. Related: Conference reports, Women's health, Pregnancy.

22nd International AIDS Conference (AIDS 2018) – second reports

24 August 2018. Related: Conference reports.

Namibia close to achieving 90-90-90 targets

24 August 2018. Related: Conference reports, Treatment access.

Dolutegravir monotherapy: still no longer recommended in either research or clinical practice

24 August 2018. Related: Conference reports, Treatment strategies.

Changing comorbidities in HIV positive people older than 60 at London clinic

24 August 2018. Related: Conference reports, Coinfections and complications.

High acceptability of annual digital (finger) exam for early detection of anal cancer in gay men >35 years old

24 August 2018. Related: Conference reports, Coinfections and complications, Cancer and HIV.

High rates of anal HPV infection in gay men using PrEP in IPERGAY: the role of vaccination

24 August 2018. Related: Conference reports, Cancer and HIV, HIV prevention and transmission.

HCV incidence and reinfection in HIV negative gay men using PrEP in the Netherlands

24 August 2018. Related: Conference reports, Hepatitis coinfection.

FDA-approved compounds that might selectively reverse HIV latency

24 August 2018. Related: Conference reports, Cure-related research.

Lack of impact on viral reservoir with α4β7 monoclonal antibody vedolizumab: macaque results not matched in humans

24 August 2018. Related: Conference reports, Cure-related research.

Janssen HIV vaccine: update from APPROACH and largescale efficacy study

24 August 2018. Related: Conference reports, HIV prevention and transmission, Cure-related research.

Viral load testing in Latin America and the Caribbean

24 August 2018. Related: Conference reports, Treatment access, Diagnostics.

Access to viral load testing increased from 14% to 61% over two years in Côte d’Ivoire

24 August 2018. Related: Conference reports, Treatment access, Guidelines.

Resolving a diagnosis for people with persistently indeterminate HIV test results

24 August 2018. Related: Conference reports, Diagnostics, HIV prevention and transmission.

10th International Workshop on HIV Paediatrics – second reports

24 August 2018. Related: Conference reports.

Dolutegravir dispersible tablets for infants and young children: early PK, safety and efficacy

24 August 2018. Related: Conference reports, Paediatric care, PK and drug interactions.

22nd International AIDS Conference (AIDS 2018) – first reports

3 August 2018. Related: Conference reports.

Caution on press conference news from AIDS 2018

3 August 2018. Related: Conference reports.

Zero HIV transmissions in PARTNER 2 study after gay couples had sex 77,000 times without condoms – an undetectable viral load stops HIV

3 August 2018. Related: Conference reports, HIV prevention and transmission.

DTG/3TC dual therapy is non-inferior to triple-ART in GEMINI study

3 August 2018. Related: Conference reports, Antiretrovirals.

Once-daily reduced dose darunavir/ritonavir (400 mg/100 mg) is non-inferior to twice-daily lopinavir/ritonavir in South African switch study

3 August 2018. Related: Conference reports, Treatment strategies.

Superior efficacy with dolutegravir-based ART compared with other regimens at 6 months: real-world data from Brazil

3 August 2018. Related: Conference reports, Antiretrovirals, Treatment access.

WHO recommends dolutegravir widely but women’s access will depend on contraception provision (2018)

3 August 2018. Related: Conference reports, Women's health, Pregnancy, Guidelines.

No additional neural tube defects among a further 170 preconception dolutegravir exposures in Botswana: Tsepamo study (July 2018)

3 August 2018. Related: Conference reports, Pregnancy.

Swifter viral load suppression with dolutegravir vs efavirenz in late pregnancy: results from DolPHIN-1

3 August 2018. Related: Conference reports, Pregnancy.

First randomised kick-and-kill cure study fails to reduce HIV reservoir: RIVER study reports vorinostat and vaccines show activity, but not enough

3 August 2018. Related: Conference reports, Cure-related research.

Using PrEP with feminising hormone therapy supports daily PrEP dosing for transwomen

3 August 2018. Related: Conference reports, PK and drug interactions, HIV prevention and transmission.

Daily and on-demand PrEP both prevent HIV in Prévenir study: high adherence by gay Parisians

3 August 2018. Related: Conference reports, HIV prevention and transmission.

AIDS 2018 online: links to selected webcasts

3 August 2018. Related: Conference reports.

10th International Workshop on HIV Paediatrics – first reports

3 August 2018. Related: Conference reports, Paediatric care.

Preconception safety signal with dolutegravir: data from the Tsepamo study

3 August 2018. Related: Conference reports, Pregnancy.

What to watch: HIV cure-related research at AIDS 2018

20 July 2018. Related: Conference reports, Cure-related research.

AIDS 2018: Programme online and late-breaker highlights announced three weeks before the conference

11 July 2018. Related: Conference reports.

19th International Workshop on Clinical Pharmacology, 22–24 May 2018, Baltimore

29 June 2018. Related: Conference reports.

Unbound dolutegravir plasma concentrations unchanged in pregnancy and standard dosing crosses the placenta in placental perfusion model

29 June 2018. Related: Conference reports, Pregnancy, PK and drug interactions.

Etravirine dispersible paediatric tablet has greater bioavailability when dispersed in water compared to swallowed whole

29 June 2018. Related: Conference reports, Paediatric care, PK and drug interactions.

Reduced exposure to elvitegravir in pregnancy: results from the PANNA Network

29 June 2018. Related: Conference reports, Pregnancy, PK and drug interactions.

Rifabutin dosed 2.5 mg/kg daily with lopinavir/r in children achieves comparable exposure to adults

29 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.

No clinically relevant reduction in oral cabotegravir when co-administered with rifabutin

29 June 2018. Related: Conference reports, PK and drug interactions.

Boosted darunavir 800/100 mg twice daily might overcome interaction with rifampicin

29 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.

Efavirenz side effects and other drug-drug interactions are common in Ugandan cohort

29 June 2018. Related: Conference reports, PK and drug interactions, Side effects.

19th International Workshop on Clinical Pharmacology, 22–24 May 2018, Baltimore

8 June 2018. Related: Conference reports.

Dolutegravir 50 mg twice daily sufficient with rifampicin but levels reduced significantly with 100 mg once daily

8 June 2018. Related: Conference reports, PK and drug interactions, TB coinfection.

Vaginal ring reduces efavirenz but not atazanavir exposures

8 June 2018. Related: Conference reports, PK and drug interactions.

Dispersible paediatric versions of dolutegravir provide higher bioavailability than immediate release formulations

8 June 2018. Related: Conference reports, Paediatric care.

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