HTB

Conference reports

Levofloxacin: safety and tolerability in HIV positive and negative children treated for MDR-TB

2016 Towards an HIV Cure Symposium, 16-17 July 2016, Durban, South Africa

17th International Workshop on Clinical Pharmacology of HIV & Hepatitis Therapy, 8-10 June 2016, Washington DC, USA

Modelling data might support use of low dose 400 mg efavirenz in pregnancy

Pharmacokinetics of antiretrovirals comparable to that in non-pregnant women from three weeks after delivery

22nd Annual BHIVA Conference, 19-22 April 2016, Manchester

New HBV drugs and non-viral liver disease in HIV positive people

Non-AIDS mortality in England and Wales in HIV positive vs general population

High prevalence of multiple high-risk HPV infections in young HIV positive gay men

Anal cancer and HPV screening in HIV positive people

Increasing demand for community treatment information services

Non alcohol fatty acid liver disease: an emerging problem

HIV positive people on ART have impaired alveolar immunity

International Liver Congress (EASL) 2016, 13-18 April 2016, Barcelona

High cure rates using generic hepatitis C drugs bought online: EASL supports lower cost access for Western countries

Studies of new generic $300 HepC combination of ravidasvir and sofosbuvir for low-income countries

23rd Conference on Retroviruses and Opportunistic Infections (CROI 2016), 22-25 February 2016, Boston

No effect of tenofovir on infant bone mineral content in African study

Use of modelling to predicting paediatric dosing of long acting antiretrovirals

Nevirapine dosing for treatment of neonates

START substudies: increased quality of life from earlier treatment but no impact on vascular function or cardiovascular markers

Six-week ledipasvir/sofosbuvir in HIV positive patients with acute HCV

6th International Workshop on HIV & Women, 20-21 February 2016, Boston

Doravirine can be co-administered with oral contraceptives

No increased risk of birth defects with darunavir: findings from the Antiretroviral Pregnancy Registry

23rd Conference on Retroviruses and Opportunistic Infections (CROI 2016), 22-25 February 2016, Boston

Dual long-acting injections of cabotegravir plus rilpivirine: 32-week results from LATTE-2 study

New NRTI MK-8591 (EFdA): weekly oral dosing and once-yearly slow-release dosing has potential for HIV treatment and PrEP

Similar viral load reductions at week 4 when dolutegravir is used with 2- or 3-drug initial ART

48-week results for NNRTI doravirine compared to efavirenz

Dramatic increase in use of oral TDF/FTC for PrEP in the US – plus a few cautions

Future oral and long-acting formulations for PrEP: pills, films, gels, injections and depots

First data on TAF as PrEP to prevent HIV infection

Long-acting cabotegravir as PrEP protects macaques against IV exposure but will need two-monthly injections

Role for maraviroc as HIV PrEP likely to need dual combinations

Dapivirine PrEP vaginal ring shows only limited PrEP protection against HIV in African women

Early data from dolutegravir use during pregnancy

Dolutegravir: 48 week results in children age 6 to 12 years old

New antiretrovirals could mean savings up to US $3 billion by 2025

Countries with lower HIV prevalence have lower ART coverage

Nigerian herbal medicines widely used by HIV positive people can contain antiretrovirals

Cure research news from CROI 2016

46th World Conference on Lung Health of the International Union Against TB and Lung Disease

Promising first results with a 9-month regimen for multidrug resistant tuberculosis in French-speaking African countries

Pharmacokinetics of old and new TB drugs for children

The REALITY trial: cotrimoxazole/isoniazid/pyridoxine tablets are bioequivalent to individual products and are acceptable to participants

BHIVA Autumn Conference 2015, 12-13 November 2015, London

Selected webcasts from BHIVA Autumn conference 2015

15th European AIDS Conference (EACS), 21-24 October 2015, Barcelona

Remarkable results with dolutegravir monotherapy

First-line ART with dolutegravir plus 3TC: 24-week early results

New European HIV guidelines (October 2015): universal ART, first-line integrase and PrEP

Impact of early ART on lung function: results on ART and COPD from START substudy

No difference in neuropsychological test results between early and delayed ART in START substudy

Immediate ART in START linked to greater bone loss over three years

Price of MDR TB drugs could be greatly reduced with competitive generic manufacture

Potential for generic prices for 12 weeks sofosbuvir treatment to drop below US $300 and daclatasvir to US $23

Achieving viral suppression with HIV multi-drug resistance: peg-interferon and valaciclovir as part of rescue therapy

French cohort of HIV transgender women highlights issues relating to HIV management

7th International Workshop on HIV Paediatrics, 17-18 July, Vancouver, Canada

Substituting lopinavir/ritonavir with efavirenz in children on stable ART

The effects of systemic efavirenz exposure, sex and age on risk of viral non-suppression

Pharmacokinetics of lopinavir/ritonavir super-boosting in infants and young children co-infected with HIV and TB

55th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), 17-21 September 2015, San Diego

No transmission of integrase-resistant HIV seen in California cohort

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